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Medicinal composition for treating osteo porosis and its formulation

A technology for osteoporosis and drugs, which is applied in drug combinations, medical preparations containing active ingredients, bone diseases, etc., can solve problems such as gastrointestinal irritation, and achieve the effect of less toxic and side effects and significant curative effect

Inactive Publication Date: 2006-08-09
罗忠
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the simple use of bisphosphonates in the treatment of osteoporosis has more obvious side effects such as gastrointestinal irritation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment I

[0008] Add starch and dextrin to 15% total cnidium coumarin, 15% epimedium total flavonoids, 10% rhizome drynaria water extract, and 60% calcium citrate malate in proportion by weight , starch slurry, magnesium stearate, and lactose are uniformly mixed, granulated, compressed, and coated to obtain a tablet of the drug combination for treating osteoporosis.

Embodiment II

[0010] 10% total cnidium coumarin, 10% epimedium total flavonoids, 5% drynaria ethanol extract, 75% calcium citrate malate, starch, starch The slurry is uniformly mixed to make a soft material, granulated, dried, granulated and filled to obtain the capsule of the osteoporosis medicine combination.

Embodiment III

[0012] 5% total coumarin of cnidium, 5% total flavonoids of epimedium, 2% ethanol extract of rhizoma drynariae, 88% calcium citrate malate, add polysorbate according to the prescription ratio -80, sorbic acid, stevioside, add water to adjust to the standard prescription amount, mix well, filter with filter paper, fill, sterilize, and get ready.

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PUM

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Abstract

The present invention relates to a medicine composition for curing osteoporosis and its preparation. Said medicine composition is formed from (by wt%) 1%-15% of cnidium seed total coumarin, 1%-15% of epimedium total flavone, 1%-10% of drynaria root extract and 60%-97% of calcium citrate malate, and its preparation has two types of solid preparation and liquid preparation.

Description

Technical field [0001] The invention relates to a drug combination for treating osteoporosis and its preparation, in particular to 1%-15% total coumarin from Cnidium mongolica, 1%-15% total epimedium flavonoids, 1%-15% by weight The drug combination composed of 10% drynaria extract, 60%-97% calcium citrate malate and two types of preparations, solid and liquid. Background technique [0002] At present, osteoporosis is a disease that reduces bone density and bone mass, which makes bones brittle and increases the chance of fracture. It is one of the most common disabling diseases in the world. Globally, one third of women over the age of 50 suffer a fracture due to osteoporosis, and the proportion among men is one fifth. There are approximately 1.7 million femur fractures worldwide each year, and it is estimated that by 2050, 6.4 million people worldwide will suffer from femoral neck fractures, 51% of which will occur in Asia. According to Chinese statistics, the incidence r...

Claims

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Application Information

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IPC IPC(8): A61K36/296A61K31/191A61P19/10
Inventor 罗忠
Owner 罗忠
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