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Compound teribinafine hydrochloride solution for animal

A technology of terbinafine hydrochloride and compound recipes, applied in the directions of skin diseases, antifungal agents, drug combinations, etc., can solve problems such as inability to treat various pathogenic infections, and achieve the effects of reducing treatment costs, short course of treatment, and significant effects

Inactive Publication Date: 2006-12-27
NANJING JINDUN ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The object of the present invention is to provide a kind of veterinary medicine that can be used clinically for the treatment of fungal skin diseases. At the same time, it has the effects of killing mites, anti-anaerobic bacteria, and relieving itching, which overcomes the disadvantage that a single drug cannot treat multiple pathogenic infections

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Recipe composition:

[0024] Terbinafine hydrochloride 1g / 100ml, metronidazole 1g / 100ml, thiabendazole 0.1g / 100ml, chlorine

[0025] Cyanothrin 0.05g / 100ml, dexamethasone 0.05g / 100ml, borneol 0.25g / 100ml.

[0026] Preparation method:

[0027] (1) Weigh 100g of terbinafine, 100g of metronidazole, 10g of thiabendazole, 5g of dexamethasone, add 3000mL of propylene glycol, heat and dissolve, cool down to room temperature, and make A solution;

[0028] (2) Take 25g of borneol and add 1000mL of absolute ethanol to dissolve it to make liquid B;

[0029] (3) Take 5 g of cypermethrin, add 1000 mL of dimethyl sulfoxide to dissolve, and make liquid C;

[0030] (4) Add liquid B to liquid A, finally add liquid C, and then add propylene glycol to a total volume of 10,000 mL.

Embodiment 2

[0032] Recipe composition:

[0033] Terbinafine Hydrochloride 10g / 100ml, Metronidazole 2g / 100ml, Thiabendazole 0.01g / 100ml,

[0034] Cypermethrin 0.5g / 100ml.

[0035] Preparation method:

[0036] (1) Weigh 1000g of terbinafine, 200g of metronidazole, 1g of thiabendazole, add 7500mL of propylene glycol and heat to dissolve, cool down to room temperature, and make A solution;

[0037] (2) Take 50 g of cypermethrin, add 2000 mL of acetone to dissolve, and make liquid C;

[0038] (3) Add liquid C to liquid A, and then add propylene glycol to a total volume of 10,000 mL.

Embodiment 3

[0040] Recipe composition:

[0041] Terbinafine Hydrochloride 5g / 100ml, Metronidazole 0.25g / 100ml, Thiabendazole 1g / 100ml,

[0042] Cypermethrin 0.25g / 100ml.

[0043] Preparation method:

[0044] (1) Weigh 500g of terbinafine, 25g of metronidazole, 100g of thiabendazole, add 6000mL of propylene glycol, heat to dissolve, cool down to room temperature, and make A solution;

[0045] (2) Take 25 g of cypermethrin, add 2000 mL of dimethyl sulfoxide to dissolve, and make liquid C;

[0046] (3) Add liquid C to liquid A, and then add propylene glycol to a total volume of 10,000 mL.

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PUM

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Abstract

The invention discloses a compound terbinafine hydrochloride solution for animals, which is prepared mainly from terbinafine hydrochloride, Metronidazole, thiabendazole and cypermethrin. The solution has substantial effect in treating pet granuloma skin diseases.

Description

technical field [0001] The invention relates to a veterinary preparation, in particular to a veterinary compound terbinafine hydrochloride solution. Background technique [0002] With the continuous improvement of people's living standards, the number of working dogs and family pet dogs and cats in China is also increasing rapidly. In the process of raising working dogs and family pet dogs and cats for a long time, many common diseases of animals have also been found. As a common disease, skin disease has attracted the attention of veterinarians in the clinical diagnosis process, and the incidence of canine skin diseases caused by fungi accounts for more than 30% of all skin diseases. a big problem. Because such diseases are related to the strong secretion of hair and sebaceous glands in dogs, and the pathogenic bacteria of fungal skin diseases are relatively complex, and they have strong drug resistance to clinically used drugs, which brings great difficulties to clinical...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/422A61P17/00A61P31/10A61K31/137A61K31/215A61K31/4164
Inventor 李忠生单军冯秀娟叶灵友刘新贵
Owner NANJING JINDUN ANIMAL PHARMA
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