High-density lipoprotein cholesterol quantitative determining method, reagent and reagent kit

Abstract

A reagent for the content of the high density lipoprotein cholesterol in the quantitative determining serum sample, consists of the reagent I and reagent II that places respectively, the reagent I contains the heteropolymer anion compound, the divalency cation salt and the decentralized surfactants; the reagent II contains the styrylphenol polyoxyethylene ether. The invention provides a reagent box with the reagent I and the reagent II, and a method for determining the high density lipoprotein cholesterol content.

Description

technical field

[0001] The invention relates to a quantitative determination method, reagent and kit for high-density lipoprotein cholesterol (HDL-C). Background technique

[0002] Lipids such as cholesterol cooperate with apoproteins in serum to form lipoproteins. Lipoproteins are classified into chylomicrons (CM), very low-density lipoprotein (VLDL), low-density lipoprotein (LDL), high-density lipoprotein (HDL), etc. according to their physical properties. A large-scale epidemiological survey in Frammingham in 1977 showed that the decrease of plasma high-density lipoprotein cholesterol (plasma HDL-C) was the main risk factor for ischemic heart disease. General attention. High-density lipoprotein (HDL) can move the cholesterol in the surrounding tissue to the liver for degradation through the action of enzymes and receptors, and at the same time inhibit cell binding and uptake of low-density lipoprotein cholesterol, and prevent the deposition of cholesterol on the artery ...

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