Reversing agent for drug-fast during treating tumor with multiple medicines

A tumor cell, multi-drug resistance technology, applied in anti-tumor drugs, drug combinations, pharmaceutical formulations, etc., can solve the problems of research reports and patent disclosures that have not been seen in reversing tumor multi-drug resistance by pregnane compounds , to achieve the effect of wide application prospects
CN1911234AInactive Publication Date: 2007-02-14广州中医药大学热带医学研究所

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
广州中医药大学热带医学研究所
Publication Date
2007-02-14
Estimated Expiration
Not applicable · inactive patent

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Abstract

A pregnane compound for reversing the resistance of cancer cells to multiple medicines is a pregnane derivative, that is, the derivative of tenacigenin B or C and the derivative of dihydrosarcostin.
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Description

technical field

[0001] The invention relates to a new tumor cell multidrug resistance reversing agent capable of producing medicine. Specifically, it relates to a derivative of Tenacigenin B (also known as Tongguang Scattering Aglycone B, or Tongguang Scattering Aglycone B, English name Tenacigenin B), and dihydroscarptinin ( Also known as Dihydrosarcosarginin, English name Dihydrosarcostin) derivatives and Tongguang scatter aglycon C (also known as Tongguang scatter aglycon C, or Tongguang scatter aglycon C, English name Tenacigenin C) derivatives The application of natural or semi-synthetic derivatives of steroid structure in the preparation of tumor cell multidrug resistance reversal agents. Background technique

[0002] Multidrug resistance (MDR) of tumor cells means that after tumor cells develop resistance to one anticancer drug, they can simultaneously develop cross-resistance to other anticancer drugs that have not been exposed to each other with different chemical ...

Claims

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