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Jingangteng solution type solid dispersion, and application

A solid dispersion and solution type technology, applied in the direction of medical preparations containing active ingredients, drug combinations, plant raw materials, etc., can solve the problems of slow dissolution rate of active ingredients, unsatisfactory curative effect, poor absorption, etc., and achieve the main drug dosage Accurate, beneficial to labor protection, and the effect of reducing environmental pollution

Inactive Publication Date: 2007-05-09
SHANGHAI INST OF PHARMA IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the preparation products currently on the market are mainly syrups, and there are also tablets, capsules, granules, etc., due to the slow and incomplete dissolution rate of active ingredients, resulting in poor absorption and unsatisfactory curative effect, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Preparation of King Kongtaw Extract:

[0030] Add 5 times the amount of 75% ethanol to the vine and soak it for 24 hours, extract it under reflux for 3 times, each time for 1 hour, combine the extracts, filter, concentrate the filtrate, dry it in vacuum, and crush it into a fine powder.

Embodiment 2

[0032] Add 100 grams of King Kong vine extract and 120 grams of polysorbate 80 to 280 grams of molten poloxamer, mix well, heat to dissolve, degas, cool to 45°C and fill with a capsule liquid filling machine Capsules 1000 capsules, the content of King Kong vine extract is 0.1 g / capsule.

Embodiment 3

[0034] Moisten 200 grams of King Kong vine extract with 20 100 grams of polysorbate, add to 200 grams of molten polyvinylpyrrolidone, mix, stir evenly, heat to dissolve, degas, cool to 45°C and fill with capsule liquid 1000 machine-filled capsules, 0.2 g / capsule of King Kong vine extract.

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PUM

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Abstract

A solid dispersed solution of bock greenbrier rhizome is proportionally prepared from bock greenbrier rhizome, solubilizer and carrier. It can be used to prepare medicines without fly dust and with high biologic utilization rate.

Description

technical field [0001] The present invention relates to a kind of diamond rattan preparation. Background technique [0002] King Kongteng is the rhizome of Liliaceae Smilax, which has the effects of clearing away heat and detoxification, reducing swelling and dispelling stagnation. It is mainly used clinically to treat lower abdominal pain, lumbago, and irregular menstruation caused by adnexal inflammation, adnexal inflammatory mass, and various gynecological inflammations. It is also used to treat rheumatic joint pain, bruises, cellulitis, gastroenteritis, etc. [0003] However, the preparation products currently on the market are mainly syrups, and there are also tablets, capsules, granules, etc., due to the slow and incomplete dissolution rate of active ingredients, resulting in poor absorption and unsatisfactory curative effect. Contents of the invention [0004] The object of the present invention is to provide a kind of rattan vine solution type solid dispersion and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/48A61P29/00A61P15/00A61P19/02A61P1/04
Inventor 顾林金沈航孝
Owner SHANGHAI INST OF PHARMA IND CO LTD