Method for preparing injuctable material for repairing bones solidified in situ from calcium alginate
An in-situ solidification, calcium alginate technology, applied in medical science, prosthesis and other directions, to achieve the effects of low energy consumption, simple formula and easy preparation process
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Example Embodiment
[0024] Example 1:
[0025] A preparation method of calcium alginate-based injectable in-situ solidified bone repair material, the preparation steps are as follows:
[0026] Step 1: Take 100 grams of deionized water, add 5 grams of sodium phosphate and 6 grams of sodium alginate powder and stir thoroughly to obtain a sodium alginate solution.
[0027] Step 2: Add 6 grams of nano-hydroxyapatite / collagen (n HAC) particles into the sodium alginate solution in the form of a slurry, and stir thoroughly to obtain a viscous suspension.
[0028] Step 3: Add 7 grams of calcium sulfate particles to the viscous suspension described in Step 2 in the form of a slurry, and stir thoroughly to obtain the calcium alginate-based injectable in-situ solidified bone repair material. It can be formed in situ within 2 hours after being injected into the body.
Example Embodiment
[0029] Embodiment two:
[0030] A preparation method of calcium alginate-based injectable in-situ solidified bone repair material, the preparation steps are as follows:
[0031] Step 1: Take 100 g of deionized water, add 5 g of sodium phosphate and 6.0 g of sodium alginate powder and stir thoroughly to obtain a sodium alginate solution.
[0032] Step 2: Add 5 grams of nano-hydroxyapatite / collagen (n HAC) particles to the sodium alginate solution in the form of a slurry, and stir thoroughly to obtain a viscous suspension.
[0033] Step 3: Add 3 grams of calcium sulfate particles to the viscous suspension described in Step 2 in the form of a slurry, and stir thoroughly to obtain the calcium alginate-based injectable in-situ solidified bone repair material. It can be formed in situ within 2 hours after being injected into the body.
Example Embodiment
[0034] Embodiment three:
[0035] A preparation method of calcium alginate-based injectable in-situ solidified bone repair material, the preparation steps are as follows:
[0036] Step 1: Take 100 g of deionized water, add 1 g of sodium phosphate and 6 g of sodium alginate powder and stir thoroughly to obtain a sodium alginate solution.
[0037] Step 2: Add 5 grams of nano-hydroxyapatite / collagen (n HAC) particles to the sodium alginate solution in the form of a slurry, and stir thoroughly to obtain a viscous suspension.
[0038] Step 3: Add 7 grams of calcium sulfate particles to the viscous suspension described in Step 2 in the form of a slurry, and stir thoroughly to obtain the calcium alginate-based injectable in-situ solidified bone repair material. It can be formed in situ within 2 hours after being injected into the body.
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