Method for preparing medical valve-attached canal by use of cow jugular vein

Abstract

The invention relates to a method for preparing medical cow neck vein valve tube, wherein it uses glutaral composite to be twisted and combined with glutaral. The invention has better organism compatibility and low cost.

Description

technical field [0001] The invention relates to a preparation method of a medical biological material, in particular to a preparation method of a bovine jugular vein valved pipeline for heart surgery. Background technique [0002] In many heart and great vessel operations, such as tetralogy of Fallot, pulmonary atresia, double outlet of right ventricle, persistent arterial trunk, transposition of great vessels combined with pulmonary artery stenosis, and aortic lesion requiring Ross operation, it is often necessary to apply belt The valve conduit reconnects the right ventricle with the pulmonary artery. Commonly used materials include autologous pericardium, allogeneic aortic valve-bearing conduits, heterogeneous materials such as porcine aortic and pulmonary artery valve-bearing conduits, artificial materials such as Gore-Tex sheets, artificially synthesized valve-bearing conduits, etc. Limitations, such as Gore-Tex sheets generally cannot reconstruct the valve structure; ...

AI Technical Summary

Problems solved by technology

Commonly used materials include autologous pericardium, allogeneic aortic valve-bearing conduits, xenogeneic materials such as porcine aortic and pulmonary artery valve-bearing conduits, artificial materials such as Gore-Tex sheets, artificially synthesized valve-bearing conduits, etc. Limitations, such as Gore-Tex sheets generally cannot reconstruct the valve structure; autologous or bovine pericardium sew valve-bearing catheters, the valve function is not ideal; porcine aortic and pulmonary artery valve-bearing catheters have been used in clinical practice, but they are prone to calcification and decay, and the service period Limited; due to the low pressure of the right heart system and slow blood flow, the thromboembolic complications of artificial valves, especially mechanical valves, are high; the allogeneic valve-bearing catheter has a history of 40 years and has achieved good results since Ross pioneered it. However, the source of homologous valved tubes is limited, and the size is not easy to match, so its clinical application is greatly limited

In recent years, foreign countries have reported that bovine jugular vein catheters with valves have been used for clinical reconstruction of the right ventricular outflow tract and achieved good results. On the other hand, after being inserted into the human body, rejection, calcification, aging, etc. will occur, which seriously affects the clinical use effect