Method for preparing medical valve-attached canal by use of cow jugular vein

A jugular vein with valve technology, applied in the field of preparation of medical biomaterials, can solve problems such as high production cost, unsatisfactory valve function, and slow blood flow

Inactive Publication Date: 2007-05-16
重庆市中山医院
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  • Summary
  • Abstract
  • Description
  • Claims
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Problems solved by technology

Commonly used materials include autologous pericardium, allogeneic aortic valve-bearing conduits, xenogeneic materials such as porcine aortic and pulmonary artery valve-bearing conduits, artificial materials such as Gore-Tex sheets, artificially synthesized valve-bearing conduits, etc. Limitations, such as Gore-Tex sheets generally cannot reconstruct the valve structure; autologous or bovine pericardium sew valve-bearing catheters, the valve function is not ideal; porcine aortic and pulmonary artery valve-bearing catheters have been used in clinical practice, but they are prone to calcification and decay, and the service period Limited; due to the low pressure of the right heart system and slow blood flow,

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0034] The bovine jugular vein valved pipeline of the present invention is prepared according to the following steps:

[0035] (1). The 2-year-old healthy yak slaughtered on the spot was collected from the slaughterhouse, and the entire jugular vein was taken under clean conditions. After washing the inner and outer walls of the vein cavity with a large amount of tap water, it was placed in a container filled with 4°C normal saline and brought back. laboratory;

[0036] (2). Immediately use a scalpel and scissors to remove the vascular sheath and excess muscle and fat tissue, and then rinse with a large amount of normal saline;

[0037] (3). Soak in Hank's solution at 4°C for 4 hours, then put it into 0.625% glutaraldehyde solution and fix it for 48 hours under the valve closed state, the temperature is 25°C;

[0038] (4). After rinsing with distilled water, soak in 1% heparin saline for 24 hours at a temperature of 25°C;

[0039](5). Rinse with distilled water, store in 0.5...

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Abstract

The invention relates to a method for preparing medical cow neck vein valve tube, wherein it uses glutaral composite to be twisted and combined with glutaral. The invention has better organism compatibility and low cost.

Description

technical field [0001] The invention relates to a preparation method of a medical biological material, in particular to a preparation method of a bovine jugular vein valved pipeline for heart surgery. Background technique [0002] In many heart and great vessel operations, such as tetralogy of Fallot, pulmonary atresia, double outlet of right ventricle, persistent arterial trunk, transposition of great vessels combined with pulmonary artery stenosis, and aortic lesion requiring Ross operation, it is often necessary to apply belt The valve conduit reconnects the right ventricle with the pulmonary artery. Commonly used materials include autologous pericardium, allogeneic aortic valve-bearing conduits, heterogeneous materials such as porcine aortic and pulmonary artery valve-bearing conduits, artificial materials such as Gore-Tex sheets, artificially synthesized valve-bearing conduits, etc. Limitations, such as Gore-Tex sheets generally cannot reconstruct the valve structure; ...

Claims

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Application Information

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IPC IPC(8): A61L27/00A61L27/38A61L33/00A61L31/16A61F2/00
Inventor 何德沛杨庆军申林赵树林
Owner 重庆市中山医院
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