Preparing method of Jade-screen micropill
A technology of jade screen and pellets, applied in the field of preparation of jade screen pellets, can solve the problems of inconvenient taking, heavy taste of traditional Chinese medicine, bad taste, etc., and achieve the effects of stable product quality, no harmful residues, and simple process.
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Embodiment 1
[0015] Weigh the prescribed amount of Radix Astragali, Fangfeng, and Atractylodes Rhizoma Rhizome, wash them, break them into pieces, extract the volatile oil, decoct the dregs of the herbs, Radix Astragali and Atractylodes Rhizoma Atractylodes Rhizome with water twice, for 1.5 hours for the first time, and 1 hour for the second time, and combine the decoctions. Filtrate, concentrate to a thick paste with a relative density of 1.15-1.25 (65-70°C), add twice the amount of 95% ethanol to ethanol precipitation, let stand for 24 hours, take the supernatant and recover ethanol to form a concentrate.
[0016] Put the blank pellet core in the coating pot, spray the above concentrate and volatile oil on the blank pellet core to make drug-containing pellets according to the following conditions: air inlet temperature: 30-60°C, pot speed 20-40rpm, spray liquid Speed: 10-100ml / min, atomization pressure 0.1-0.2mpa.
[0017] The drug-containing pellets are placed in a coating pot, and the ...
Embodiment 2
[0019] Weigh the prescribed amount of Radix Astragali, Fangfeng, and Atractylodes Rhizoma Rhizome, wash them, break them into pieces, extract the volatile oil, decoct the dregs of the herbs, Radix Astragali and Atractylodes Rhizoma Atractylodes Rhizome with water twice, for 1.5 hours for the first time, and 1 hour for the second time, and combine the decoctions. Filtrate, concentrate to a thick paste with a relative density of 1.15-1.25 (65-70°C), add twice the amount of 95% ethanol to ethanol precipitation, let stand for 24 hours, take the supernatant and recover ethanol to form a concentrate.
[0020] Take the above concentrated solution, add lactose, starch, microcrystalline cellulose, sodium carboxymethyl starch, talcum powder, silicon dioxide, soft material made of 90% ethanol, extrude into strips through a hole diameter of 0.6-1.0 mm, and place Spherify in the spheronizer, the spheronization speed is 100-500rpm, put it in a 40°C oven and dry it, then take it out to form u...
Embodiment 3
[0022] Example 3: Weigh the prescribed amount of Radix Astragali, Fangfeng, and Atractylodes Rhizoma, wash them, break the Radix Fangfeng, extract the volatile oil, decoct the dregs of the herbs, Radix Astragali and Atractylodes Rhizome with water twice, for 1.5 hours for the first time, and 1 hour for the second time. Combine the decoctions, filter, concentrate to a thick paste with a relative density of 1.15-1.25 (65-70°C), add twice the amount of 95% ethanol to precipitate, let stand for 24 hours, take the supernatant and recover the ethanol to form a concentrate.
[0023] Put the blank ball core in the coating pot, according to the following conditions: air inlet temperature: 30-60°C, pot speed: 20-40rpm, spray speed: 4-200ml / min, atomization pressure: 0.1-0.2mpa, put the above The concentrated solution and volatile oil are sprayed on the blank pellet core to make drug-containing pellets.
[0024] Put the drug-containing pellets in the coating, spray the above-mentioned ex...
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