Hormonal contraceptive product

a technology of hormones and products, applied in the field of hormone-based contraceptives, can solve the problems of malignant growth, sequential products used in substitution therapy are particularly unsuitable for contraception, and unsuitable ovulation inhibition inhibitors

Inactive Publication Date: 2003-04-17
WYETH LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Only in the case of substitution products in the menopause of older women have hormones been administered throughout the cycle, e.g. in the sequence 10 days estrogen product, 11 days combination of estrogen and gestagen product, 7 days estrogen product, 7 days estrogen product in a particularly low dosage, but said substitution products are unsuitable for ovulation inhibition.
The sequential products used in substitution therapy are in particular unsuitab...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 2

[0053] For contraceptive treatment use was made of a product which per daily unit in table form contains 0.5 mg of estriol and 2 mg of chlormadinone acetate. It is noteworthy that estriol can be used in a concentration range of 0.5 to 3 mg and chlormadinone acetate in a concentration range of 0.75 to 5 mg. The product was administered for 12 months without any taking interval. The mode of action corresponded to that of example 1.

example 3

[0054] For contraceptive treatment use was made of a product which in each daily unit in tablet form contained 0.5 mg of estradiol valerate and 2 mg of lynestrenol. It is noteworthy that estradiol valerate can be used in a concentration range of 0.5 to 5 mg and lynestrenol in a concentration range of 0.5 to 4.5 mg. The product was administered for 12 months without any taking interval. The mode of action corresponded to that of example 1.

example 4

[0055] For contraceptive treatment use was made of a product containing per daily unit in tablet form 7.5 .mu.g of ethinyl estradiol and 75 .mu.g of desogestrel. It is noteworthy that desogestrel can be used in a concentration range of 50 to 200 .mu.g. The product was administered for 12 months without any taking interval. The mode of action corresponded to that of example 1.

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PUM

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Abstract

The present invention relates to a hormonal contraceptive product having two hormonal components, an estrogen and a gestagen, and a method for the continuous suppression of the menstrual cycle by uninterrupted administration of the product of the invention.

Description

[0001] The application is a continuation of U.S. application Ser. No. 09 / 508,648, filed Jun. 5, 2000, which is the U.S. National Phase under 35 U.S.C. .sctn.371 of International Application PCT / DE98 / 02636, filed Sep. 11, 1998, which claims priority to German Application No. DE 19739916.9, filed Sep. 11, 1997.BACKGROUND OF THE INVENTION 1. Field of the Invention[0002] The present invention relates to a hormonal contraceptive product with two hormonal components, the use thereof and a hormonal contraception process.[0003] 2. Description of the Related Art[0004] Since hormonal contraceptives became available in the 1960's, a number of hormonal components have been investigated with regards to their suitability in the most varied administration diagrams. A fundamental subdivision into combination and sequential products is possible.[0005] For example, if the desired cycle time is 28 days, in the case of the known combination products administration takes place over 21 days in a constant...

Claims

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Application Information

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IPC IPC(8): A61K31/56A61K31/565A61K31/57A61K45/06A61P5/24A61P15/18A61P19/10A61P35/00G06F17/00
CPCA61K31/565A61K31/57A61K45/06Y10S514/841Y10S514/843A61K2300/00A61P15/18A61P19/10A61P35/00A61P5/24
Inventor HESCH, ROLF-DIETER
Owner WYETH LLC
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