Last-chance quality check and/or air/pathogen filter for infusion systems

Inactive Publication Date: 2005-09-22
NXSTAGE MEDICAL
View PDF22 Cites 97 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0038] 4. filtration using filters using a combination of adsorption and blocking mechanisms to provide an optimal balance between pressure drop across the filter media and the need to block pyrogen particles, preferably with a charged nylon membrane, which attracts endotoxins thereby helping to block them and having an approximately 0.2 micron pore size.
[0039] Generally replacement fluid is heated before being infused into a patient. This is often accomplished by passing the fluid through a heater with enough heating capacity to heat the fluid as it is being infuse

Problems solved by technology

But small pore size implies high pressure dro

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Last-chance quality check and/or air/pathogen filter for infusion systems
  • Last-chance quality check and/or air/pathogen filter for infusion systems
  • Last-chance quality check and/or air/pathogen filter for infusion systems

Examples

Experimental program
Comparison scheme
Effect test

Example

[0053] Referring to FIG. 1, a filter 160 filters fluid from a source of fluid 150 to generate a batch of infusible replacement fluid 130. The filter 160 may be, and preferably is, a microporous filter that blocks pyrogens and allows the passage of dissolved electrolytes and water. The latter may provide an infusible fluid free of all pyrogens, however, in practice, the pyrogen concentration must be reduced, but not necessarily eliminated since total elimination is not practical. The most common type of pyrogen is endotoxins, which may be present even in sterilized fluids.

[0054] In hemofiltration, a large quantity of fluid is drawn from the patient and replaced with replacement fluid. Compared to dialysis, the quantity actually removed and replaced with replacement fluid tends to be high. As a consequence, it is desirable to provide replacement fluid that has a lower concentration of pyrogens than may be allowed in other infusible fluids and what may cross the membrane of a dialysis...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

Blood treatment system and method for high rate hemofiltration ensures against pyrogenic patient reaction by providing various mechanisms for filtering replacement fluid to remove endotoxins and other safety features including detecting incorrect fluid administration.

Description

BACKGROUND OF THE INVENTION [0001] During hemofiltration, hemodialysis, hemodiafiltration, ultrafiltration, and other forms of renal replacement therapy, blood is drawn from a patient, passed through a filter, and returned to the patient. Depending on the type of treatment, fluids and electrolytes are exchanged in the filter between a dialysate and / or extracted from the blood by filtration. One effect may be a net loss of fluid and electrolytes from the patient and / or exhaustion of dialysate, with a concomitant need for its replenishment, again depending on the type of treatment. To replace fluid lost from the patient and keep the patient from dehydrating, replacement fluid may be injected into the patient at a rate that matches a rate of loss, with an adjustment for a desired net change in the patient's fluid complement. To replace exhausted dialysate, fresh dialysate is continuously circulated through the filter. [0002] Presently methods to produce large volumes of dialysate from ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61FA61M1/34A61M37/00C02F1/44
CPCA61L2/0017A61M1/1656B01D61/32A61M2205/75A61M1/3455A61M1/3462A61M1/3458A61M1/3465A61M1/1668A61M1/1658A61M1/1664A61M1/3401
Inventor BURBANK, JEFFREY H.BRUGGER, JAMES M.
Owner NXSTAGE MEDICAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap