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Material delivery system

a material delivery and material technology, applied in balloon catheters, medical science, surgery, etc., can solve the problems of rhinitis, nausea, weight loss and lethargy, and the wall of the artery is re-inserted into the lumen, and achieves the effect of relieving rhinitis

Inactive Publication Date: 2006-08-24
BY PASS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0018] In an exemplary embodiment of the invention, a cytotoxic agent is injected into a target tissue. Optionally the target tissue is a portion of a blood vessel wall. Optionally the blood vessel is a pulmonary vein. Optionally, the injection causes ablation of a portion of the vessel wall. Optionally, the injection prevents transmission of an electric signal. Optionally, the velocity of injected material may reach 20 m / s, 30 m / s, 50 m / s, 100 m / s, 150 or 200 m / s or smaller, intermediate or larger speeds. In an exemplary embodiment of the invention, the cytotoxic agent contains an alcohol, optionally ethanol.
[0098] Optionally, the body cavity is a nostril and / or adjoining nasal sinuses and the method provides relief from rhinitis.

Problems solved by technology

One problem with this method is restenosis, in which the artery responds to the PTCA procedure by inflammation and inward growth.
Another problem is collapse of the wall of the artery back into its lumen.
Some problems have been reported with these methods, for example, thrombosis formation.
Systemic administration of these compounds causes undesirable side effects such as nausea, hair loss, appetite suppression, weight loss and lethargy.
In additional clinical scenarios, a mucosal layer covering cells lining a lumen reduces a potential efficacy of “washing”.

Method used

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  • Material delivery system
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Examples

Experimental program
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Embodiment Construction

Overview

[0182]FIG. 1 shows a flowchart of a method and FIGS. 2A-2E illustrate the acts of the method, of applying material(s) to and / or driving material(s) into the walls of a blood vessel, in accordance with an exemplary embodiment of the invention. FIGS. 2A-2E are discussed in parallel with the description of FIG. 1. Variations on the devices and / or methods are described following.

Exemplary Method

[0183]FIG. 1 is a flowchart 100 of a method of treating blood vessels, in accordance with an exemplary embodiment of the invention.

[0184] At 102, a narrowing or other problem in a wall 204 of a blood vessel 200 (FIG. 2A) is identified. Optionally, the narrowing is a plaque deposit 206, for example, a deposit with a calcified filling 202.

[0185] At 104, a catheter treatment system 210 (FIG. 2B) is inserted into the body and guided to the narrowing. Optionally, system 210 is used also to identify the problem, for example, including a contrast material port (not shown) or an imager (no...

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PUM

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Abstract

A method for injecting a therapeutic agent into a target tissue, the method comprising: (a) providing an expandable member; (b) positioning said expandable member in proximity to the target tissue; (c) Introducing the therapeutic agent into the expandable member until a desired pressure is achieved; and (d) creating a plurality of small apertures in the expandable member.

Description

RELATED APPLICATIONS [0001] The present application is a continuation in part of PCT application IL / 2005 / 000749 filed on Jul. 14, 2005 which claims the benefit under 119(e) of 60 / 587,335 filed Jul. 14, 2004, 60 / 599,884 filed Aug. 10, 2004, 60 / 603,262 filed Aug. 23, 2004 and 60 / 675,477 filed Apr. 28, 2005, an inventor common to all of these applications is Mordechay Beyar, the disclosures of which are incorporated herein by reference.FIELD OF THE INVENTION [0002] The present invention relates to the delivery of materials, for example, high speed intrabody needle-less injection. BACKGROUND OF THE INVENTION [0003] A common treatment for a blocked artery, especially a coronary artery, is PTCA, in which a balloon is inflated inside the lumen of the artery, causing the lumen to increase, while compressing the blockage and / or forcefully expanding the artery. One problem with this method is restenosis, in which the artery responds to the PTCA procedure by inflammation and inward growth. Ano...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61M29/00A61F2/958
CPCA61F2/958A61M25/10A61M25/1027A61M2025/105A61M2025/1088A61B2018/00023A61B2018/00029A61B2018/00238A61B2018/00345A61B2018/00642A61B2018/0066A61B2018/00672A61B2018/00678A61B2018/00708A61B2018/00744A61B2018/00863A61B2018/2211A61B2018/266
Inventor BEYAR, MORDECHAYGLOBERMAN, ORENKELLER, RAMI
Owner BY PASS
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