Controlled release biocidal salts

a biocidal salt and controlled release technology, applied in the direction of meat/fish preservation using chemicals, peptides, containers preventing decay, etc., can solve the problems of not being natural, many presently-used preservatives are not green and are not natural, and commonly-used preservatives do not possess controlled release properties

Inactive Publication Date: 2010-07-08
NEVADA NATURALS
View PDF9 Cites 33 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0005]It is an object of the invention to provide controlled release biocidal salts that are environmentally

Problems solved by technology

Many presently-used preservatives are not green and are not natural or naturally-derived and many are not approved for food use.
Furthermore, commonly-used preser

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

example 1

Antimicrobial Activity of LAE Laurate

[0053]0.1 g of Nα-lauroyl-L-arginine ethyl ester laurate (LAE laurate) was dissolved in 100 g of 1,2-pentanediol so as to provide a solution containing 1,000 parts per million of the salt. The solution was then applied to soya agar plates which had been previously inoculated with the bacteria indicated below and subsequently incubated at 37° C. for 48 hours. The results are set forth below in Table 1.

TABLE 1Antimicrobial Activity of LAE LaurateMinimum Inhibitory Concentration, ppmGram Positive BacteriaBacillus subtilusStaphylococcus aureusGram Negative BacteriaEnterobacter aerogenes

example 2

Antimicrobial Activity of Compounded Films

[0054]Two beef loins from a slaughterhouse were tested in a heat-sealed package simulating food packaging. The linear low density polyethylene film was compounded with 1% w / w LAE lactate biocidal salt of the invention. The results are reported in Table 2 below. The log colony forming units (“CFU”) reduction values for bacteria that are part of the background flora of raw meat for both samples are 42 days indicate that there is a release of the salt of the invention from the polyethylene film to the surrounding beef surfaces.

TABLE 2Antimicrobial Activity of Compounded FilmsDay 42Day 42Log CFU / g, dayslog reduction% reductionSample714212842vs. controlvs. controlcontrol2.624.685.637.067.2400LAE2.313.683.975.325.571.6797.9lactate

example 3

Beef Purge Test

[0055]Two beef tenderloins containing a large quantity of purge (i.e., liquid surrounding raw meats; meat soaker pads were used to trap such liquids to the extent possible) were purchased at a local store. The purge was isolated from the packages and transferred to a series of test tubes and 10 ml of purge were placed in each test tube. To the test tubes was added 0.5 g of either LAE hydrochloride or LAE mono-laurate salts. The samples were mixed in a vortex mixer and serial dilutions were then plated on petrifilm for readings at time zero. The test tubes were then placed in the refrigerator and were again plated at 24 hours and 48 hours. The beef purge contained naturally-occurring aerobic bacteria. The goal is to have >99% reduction of the bacteria after 48 hours. LAE hydrochloride was tested at 0.5 g / 10 ml w / v. Both samples showed >99% reduction in bacterial counts after 48 hours. The results are reported in Table 3 set forth below. Note that the symbol “E” set for...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Fractionaaaaaaaaaa
Fractionaaaaaaaaaa
Fractionaaaaaaaaaa
Login to view more

Abstract

A controlled release biocidal salt of a first component comprises a cation of a Nα—(C1-C22)alkanoyl di-basic amino acid alkyl(C1-C22)ester cationic biocidal molecule and a second component comprising an anion of a monomeric anionic molecule having insignificant biocidal activity. The salt is characterized such that when the salt is exposed to an aqueous medium, the salt partially dissolves thereby releasing biocidal ions in an amount sufficient to exceed the MIC or MBC of a target bacteria being controlled, and further characterized as leaving a residual reservoir of undissolved salt capable of releasing more biocidal ions as the salt is consumed or otherwise removed from the environment encompassing the target bacteria. The preferred cationic biocidal molecule comprises Nα-lauroyl-L-arginine ethyl ester (“LAE”).

Description

REFERENCE TO RELATED APPLICATIONS[0001]This application claims the benefit of application Ser. No. 12 / 589,155, filed Oct. 19, 2009 (claiming the benefit of provisional application Ser. No. 61 / 196,455, filed Oct. 17, 2008) and also claims the benefit of application Ser. No. 11 / 633,231, filed Dec. 4, 2006 (claiming the benefit of provisional application Ser. No. 60 / 748,719 filed Dec. 9, 2005). Further, this application is a continuation-in-part of application Ser. No. 10 / 770,248 filed Feb. 2, 2004 (claiming the benefit of provisional application 60 / 445,104 filed Feb. 6, 2003) now abandoned and is also a continuation-in-part of application Ser. No. 10 / 972,567 filed Oct. 25, 2004 as a continuation-in-part of said application Ser. No. 10 / 770,248. Further, this application is a continuation-in-part of application Ser. No. 12 / 586,695 filed Sep. 26, 2009. This application is also a continuation-in-part of application Ser. No. 10 / 972,567 filed Oct. 25, 2004 as a continuation-in-part of said ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A01N37/12C07C279/14C07C229/26C07D233/64C07D209/20
CPCA01N47/44A01N37/44A01N47/14A01N43/82A01N43/40A01N37/36A01N37/02A01N33/12A01N43/38A01N43/50A23B4/20A23L3/34635A23L3/3508A23L3/3526A23V2002/00B65D81/28Y10T428/662Y10T442/2525A01N37/06A01N37/38A01N37/40
Inventor SAWYER, ANTHONY J.STOCKEL, RICHARD F.
Owner NEVADA NATURALS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap