Purification of and air methods of making and using the same

a technology of air purifier and purification method, which is applied in the direction of disease, other medical devices, efficient regulation technologies, etc., can solve the problems of high cost of ivf, not typically covered by medical insurance, and inability to protect human embryos from environmental toxins, etc., and achieve high purity and method of making

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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0007]Accordingly, air characterized by very high purity and methods of making and using such air, are provided.

Problems solved by technology

However, IVF is very expensive and is not typically covered by medical insurance.
It is financially prohibitive for most people to undergo multiple rounds of IVF.
Human embryos have no means of protection or filtration against environmental toxins and pathogens.
Although airborne contaminants can adversely affect embryogenesis, surprisingly little emphasis has been placed on optimizing laboratory air quality during the last three decades in which IVF has been available as a treatment for infertility.
Existing filtration devices have been found insufficient to optimize air quality to truly acceptable levels for IVF.
Additionally, some filters produce by-products or other contaminants that actually detract from the quality of the air in an IVF laboratory.
For example, carbon filters can create carbon dusting that is harmful to the IVF process.

Method used

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  • Purification of and air methods of making and using the same
  • Purification of and air methods of making and using the same
  • Purification of and air methods of making and using the same

Examples

Experimental program
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example 1

[0050]An embodiment of the air purifier described herein was installed in an IVF laboratory beta site. Prior to that installation, the laboratory used two Coda® Systems. Each Coda® System included, from an upstream towards a downstream direction: (1) particulate filtration; (2) carbon and KMnO4 filtration; and (3) HEPA filtration. Prior to installation of the aforementioned embodiment of the air purifier, clinical pregnancy rates at the laboratory were 36.4%, which is near the national average of about 38%. The embodiment of the air purifier described herein that was installed in the laboratory included, from an upstream towards a downstream direction: (1) particulate filtration (located upstream in the air handler unit); (2) carbon and KMnO4 filtration; (3) UV filtration; (4) carbon and KMnO4 filtration; and (5) HEPA filtration. After installation of the aforementioned embodiment of the air purifier, clinical pregnancy rates at the laboratory jumped to 67.4% based on a patient popu...

example 2

[0053]The following three charts provide data from independent third party testing of air quality in an IVF laboratory. Common to all three charts is the following terminology: (1) “Source Air”—the air going into an IVF laboratory prior to entering a respective filtration system; (2) “IVF Laboratory”—the ambient air within the IVF laboratory; (3) “TVOC”—total volatile organic compounds, measured in “ppb,” or parts per billion; (4) “Biologicals”—biological contaminants, including spores, measured in “CFU / M3,” or colony forming units per cubic meter; and (5) “Particulate”—the number of particles per cubic foot having nominal sizes of 0.3 μm and 0.5 μm. These measurements were made using measuring devices and techniques described supra.

CHART NO. 1IVF LaboratoryUsing Two (2) CODA Air Filtration SystemsSource AirIVF LaboratoryTVOC1324 ppb1372 ppbBiologicals469 CFU / M31778 CFU / M3Particulate2,318,66311,6420.3 μm0.3 μmparticles per ft3particles per ft31,874,7899,4210.5 μm0.5 μmparticles per ...

example 3

[0059]An embodiment of the air purifier described herein was installed in an IVF laboratory beta site. This embodiment included, from an upstream towards a downstream direction: (1) particulate filtration (located upstream in the air handler unit); (2) carbon and KMnO4 filtration; (3) UV filtration; (4) carbon and KMnO4 filtration; and (5) HEPA filtration.

[0060]A catastrophic load of VOCs was accidentally introduced into the building that housed the IVF laboratory. In particular, a contractor had poured floor sealant on a large floor surface area in a room just adjacent to the IVF laboratory. The floor sealant comprised 10% xylene and 40% acetone. Both xylene and acetone are highly embryotoxic. While staff outside of the IVF laboratory developed nausea and intense headaches from the fumes, the aforementioned embodiment of the air purifier protected the embryos and staff within the IVF laboratory. TVOC testing before and during the accident demonstrated that despite over 6000 ppb TVO...

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Abstract

Purified air is provided, having a TVOC content of from less than 5 ppb to about 500 ppb, a Biologicals content of from less than 1 CFU/M3 to 150 CFU/M3 and a Particulate content of from about 1,000 0.3 μm particles per ft3 to about 50,000 0.3 μm particles per ft3, or from about 600 0.5 μm particles per ft3 to about 500,000 0.5 μm particles per ft3.

Description

BACKGROUND OF THE INVENTION[0001]This application is a continuation-in-part of U.S. patent application Ser. No. 13 / 244,973, filed on Sep. 26, 2011, which is a continuation of U.S. patent application Ser. No. 12 / 732,246, filed on Mar. 26, 2010. International Application No. PCT / US2011 / 029567, filed on Mar. 23, 2011, claims priority to U.S. patent application Ser. No. 12 / 732,246.FIELD OF INVENTION[0002]This invention relates to devices and methods for the filtration and purification of air. More particularly, this invention relates to air purifiers capable of providing a level of air quality suitable for environments that are highly sensitive to airborne contaminants, e.g., in vitro fertilization laboratories or other medical environments. Further, the invention may be adapted for use in any substantially enclosed environment, including, but not limited to, homes, residential buildings, commercial buildings, hotels, cars, buses, trains, airplanes, cruise ships, educational facilities,...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61L9/20A61B17/425C09K3/00F24F8/22
CPCA61L9/20B01J20/0222A61L2209/16B01D46/0036B01D46/521B01D53/007B01D53/02B01D2253/102B01D2253/112B01D2257/708B01D2257/91B01D2259/4508B01D2259/804B01D2267/40B01J20/20F24F3/16F24F5/0089F24F11/0008F24F11/0012F24F11/0015F24F2003/1667B01J20/04B01D2255/2073B01D2259/4533B01J2220/42F24F2011/0032B01J20/28052Y02B30/78A61L2209/14F24F11/30F24F2110/10F24F2110/20F24F2110/66F24F8/22Y02B30/70F24F11/52F24F11/39F24F11/74B01D53/04F24F8/158A61B17/43B01D46/0028
Inventor WORRILOW, KATHRYN C.
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