Quinone derivatives for use in the modulation of redox status of individuals

a technology of redox status and derivatives, which is applied in the direction of peptide/protein ingredients, extracellular fluid disorder, metabolic disorder, etc., can solve the problem of not clear treatment of diseases involving oxidative stress, and achieve the effects of restoring redox balance and metabolic control, reducing glutathione, and increasing the glutathione charge coupl
US20150216820A1Inactive Publication Date: 2015-08-06BIOELECTRON TECH CORP
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
BIOELECTRON TECH CORP
Publication Date
2015-08-06
Estimated Expiration
Not applicable · inactive patent

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Abstract

Methods of modulating, adjusting, and maintenance of the glutathione redox status of an individual, or cell, tissues, bodily fluids, or body compartments of the individual, are disclosed, as are compositions suitable for such modulating, adjusting, and maintenance. The modulation or adjustment is achieved by altering the amounts of reduced glutathione versus oxidized glutathione in the individual, or cells, tissues, bodily fluids, or body compartments of the individual. Modulation, adjustment, and maintenance of the redox status of an individual enables treatment, prevention or suppression of diseases or symptoms associated with diseases. These methods are achieved by using quinone derivatives.
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Description

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application claims priority benefit of U.S. Provisional Patent Application No. 61 / 698,431 filed Sep. 7, 2012, and of U.S. Provisional Patent Application No. 61 / 792,797 filed Mar. 15, 2013. The entire contents of those applications are hereby incorporated by reference herein.TECHNICAL FIELD OF THE INVENTION

[0002] The application discloses compositions and methods useful for modulation of the glutathione redox status and redox potential of an individual, useful in treatment, prevention, or suppression of diseases, by administering redox-active compounds (such as tocotrienol quinones, for example, alpha-tocotrienol quinone).BACKGROUND

[0003] A proper balance between oxidation and reduction reactions in cells, tissues, and organisms is vital for health. Maintenance of such a proper redox balance is, for example, critical for proper functioning of processes such as glycolysis, the citric acid cycle, and oxidative phosphorylation, which depen...

Claims

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