Formulations for control and repellency of biting arthropods

a technology of repellency and formulation, applied in the field of repellent formulations, can solve the problems of unseemly bad smell, potentially life-threatening illness, itching sensation and often a rash,

Inactive Publication Date: 2018-08-02
BEDOUKIAN RES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0020](II) any synergistic combination of nootkatone in combination with one or more repellents selected from the group consisting of N,N-Diethyl-3-methylbenzamide, para-menthane-3,8-diol (PMD), Picaridin, ethyl 3-[acetyl(butyl)amino]propanoate (IR3535), and other nitrogen-containing repellents including amines, a...

Problems solved by technology

The blood sucking of mosquitoes results in an itching sensation and often a rash.
Also, many mosquitoes cause potentially life-threatening illness.
DEET®, namely N,N-Diethyl-3-methylbenzamide, is widely used against biting arthropods and insects, but is characterized by an unseemly bad smell, is not particularly long lasting in its effect and it dissolves plastics.
Moreover, several safety questions have been rai...

Method used

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  • Formulations for control and repellency of biting arthropods
  • Formulations for control and repellency of biting arthropods
  • Formulations for control and repellency of biting arthropods

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Embodiment Construction

[0036]As used herein, the term “synergistic” refers to any combination of compounds and / or repellents that produces a combined effect greater than, preferably significantly greater than, the sum of their separate effects. In the formulations of this disclosure, the combined effect is greater repellency or protection time.

[0037]As used herein, the term “nootkatone” refers to any individual enantiomer of nootkatone, namely (−)-(4S,4aR,6S)-nootkatone or (+)—(4R,4aS,6R)-nootkatone, or a combination of the enantiomers. The (−)—(4S,4aR,6S)-nootkatone enantiomer has a weak woody (vetiver note), no grapefruit character, and an odor threshold of 600000 ppb. The (+)-(4R,4aS,6R)-nootkatone enantiomer has a strong grapefruit odor, and an odor threshold of 800 ppb.

[0038]Control and repellency of biting arthropods, and especially ticks, mosquitoes and bed bugs, is obtained by contact of the biting arthropods with biting arthropod repellent formulations based on nootkatone acting in combination, o...

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Abstract

This disclosure relates to a method for the control or repellency of biting arthropods. The method comprises bringing the biting arthropods into contact with a biting arthropod repellent formulation. The biting arthropod repellent formulation comprises nootkatone in combination, or in synergistic combination, with skin or plant derived compounds and compounds structurally similar to them (e.g., ketones, cyclic ketones, esters, gamma or delta lactones, and branched and/or unsaturated carboxylic acids), and/or one or more repellents selected from the group consisting of DEET®, para-menthane-3,8-diol (PMD), Picaridin, ethyl 3-[acetyl(butyl)amino]propanoate (IR3535), and other nitrogen-containing repellents including amines, amides, and nitrogen-containing heterocyclic compounds. This disclosure also relates to a biting arthropod repellent formulation comprising nootkatone in combination, or in synergistic combination, with the skin or plant derived compounds and compounds structurally similar to them, and/or the one or more repellents.

Description

RELATED APPLICATION[0001]This application claims the benefit of U.S. Patent Application Ser. No. 62 / 451,444, filed Jan. 27, 2017, which is incorporated herein by reference in its entirety.BACKGROUND OF THE DISCLOSURE1. Field of the Disclosure[0002]This disclosure relates to repellent formulations of compounds used as agents to control and repel biting arthropods, and especially ticks, mosquitoes and bed bugs. Also, this disclosure relates to repellent formulations of compounds used synergistically as agents to control and repel biting arthropods, and especially ticks, mosquitoes and bed bugs.2. Description of the Related Art[0003]Many mammals, including humans, have suffered the action of mosquitoes and other biting insects. The blood sucking of mosquitoes results in an itching sensation and often a rash. Also, many mosquitoes cause potentially life-threatening illness. Aedes aegypti can transmit dengue fever, yellow fever, and Zika virus, Anopheles quadrimaculatus can transmit mala...

Claims

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Application Information

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IPC IPC(8): A01N35/06A01N49/00A01N31/06A01N37/42A01N37/36A01N37/18A01N43/16A01N43/08
CPCA01N35/06A01N49/00A01N31/06A01N43/08A01N37/36A01N37/18A01N43/16A01N37/42Y02A50/30A01N31/02
Inventor BEDOUKIAN, ROBERT H.
Owner BEDOUKIAN RES
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