Composition comprising aqueous medium with reduced size water clusters to improve bioavailability of the aqueous medium and methods for making and using the compositions

Abstract

The invention relates to products by processes, product compositions, product formulations and product uses that are all related to reduced ultrapure water cluster sizes in an aqueous composition containing a non-H2O substance in the reduced size water clusters in order to improve bioavailability of the aqueous composition. The invention processes use higher flow rate of the blended aqueous composition from a jet openings of a nozzle inside the hollow cylinder to reduce sizes of the ultrapure water clusters in the blended aqueous composition of the non-H2O substance to less than 300 nanometers.

Description

BACKGROUND OF THE INVENTION[0001]The common 2D view of H2O is illustrated in FIG. 1 where two (2) hydrogen atoms 401, 404 are chemically bonded to one (1) oxygen atom 402 at a 106 angle to makes make a polar molecule with an electronic size (dashed line) of 0.28 by 0.32 nanometers. H2O is known to ionize to hydronium cations and hydroxonium anions (OH−). The hydronium ion is often given the empirical molecular formula H3O+ and depicted in 2D as an oxygen atom 400 bonded to three hydrogen atoms 401, 402, and 403 with the dashed line 404 defining its 2D electronic size (see FIG. 4). The hydroxonium ion (traditionally called hydroxide ion with molecular formula OH−) is depicted in FIG. 3 as an oxygen atom 301 and a hydrogen atom 302.[0002]Each H2O molecule can form up to four hydrogen bonds in liquid water. FIG. 2 illustrates a hydrogen bond between two (2) water molecules. Oxygen atom 202 is hydrogen bonded to water molecule hydrogen atom 201. Most models for intermolecular water H-bo...

AI Technical Summary

Benefits of technology

The present invention is a process for improving the bioavailability of an aqueous composition containing a non-H2O substance. This is achieved by adding the non-H2O substance to ultrapure water and then pumping the mixture through a nozzle with one or more jet openings. This process reduces the size of water clusters in the aqueous composition, resulting in a smaller water cluster size. Ultrapure water is important because it avoids the issue of water clusters, which can reduce the effectiveness of the non-H2O substance. The reduced size water clusters containing the non-H2O substance can then be used to improve bioavailability.

Problems solved by technology

The obvious limitation of the Keutsch study is probably that he studied only UPW which is never the state of biological water.

Unfortunately, regarding aqueous solutions in the liquid state—the structural information that can be obtained from diffraction studies on liquid species is limited because of the continual translational and rotational movement of the molecules (taken from Plumridge & Waigh, 2002).

(3) A polar residue that is geometrically incompatible with structured water may be transmitted by water molecules to neighboring groups and lead to a disruption of hydrophobic bonding.

However, when an additional non-water substance is present or water is confined, then the hydrogen bonding should no longer be randomized and merely tetrahedral.

If a substance has properties that do not allow it to overcome the cohesive forces between the water molecules, then the substance appears to be insoluble.

Many non-polar substances such as fats and oils are often poorly soluble (insoluble or immiscible) in water.

These significant differences may result in separate or various degrees of aggregation or clustering of molecules having intermolecular H-bonds.

Now add the complexity that water compositions prepared for human use and consumption often contain minerals and other non-H2O substances.

Thus, a water composition prepared for human consumption can have known ingredients, be produced by a novel process, and the water composition can have new and unpredictable properties.

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