Photoacoustic assay and imaging system

a technology of photoacoustic assay and imaging system, which is applied in the field of non-invasive invivo methods and equipment, can solve the problems of relatively high cost of measurement, relatively complicated methods and equipment, and general invasiveness of methods and associated devices, and achieves the effect of increasing path length, accurate measurement, and increasing accuracy of a determination of the speed of sound
US6846288B2Inactive Publication Date: 2005-01-25PHC HLDG CORP
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Patent Information

Authority / Receiving Office
US Ā· United States
Current Assignee / Owner
PHC HLDG CORP
Publication Date
2005-01-25
Estimated Expiration
Not applicable Ā· inactive patent

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Abstract

A method for assaying a component of a localized region of interest in a body comprising: illuminating the region with at least one pulse of radiation having a wavelength at which the radiation is absorbed by the component to generate a change in an acoustic property of the region; transmitting ultrasound so that it is incident on the region; measuring at least one effect of the change on the incident ultrasound; using the measured at least one effect to determine an absorption coefficient for the radiation in the region; and using the determined absorption coefficient to determine concentration of the component in the region.
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Description

RELATED APPLICATIONSThe present application claims priority under 35 U.S.C. Ā§120 to Israel Patent Application No. 138073, which was filed on Aug. 24, 2000.FIELD OF THE INVENTIONThe invention relates to non-invasive in-vivo methods and apparatus for determining the concentration of a substance in a body and for determining the concentration of the substance as a function of position in the body.BACKGROUND OF THE INVENTIONMethods and apparatus for in-vivo and in-vitro measurements of blood glucose levels are known in the art. Generally, the methods and apparatus are relatively complicated and measurements of a person's blood glucose levels are usually performed in a clinic or laboratory with the aid of a technician and costs of the measurements are relatively high.Methods and apparatus for determining blood glucose levels for use in the home, for example by a diabetic who must monitor blood glucose levels frequently, are available. These methods and associated devices are generally in...

Claims

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