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Skin care compositions

a technology of skin care compositions and retinoids, which is applied in the direction of biocide, hair cosmetics, body powders, etc., can solve the problems of skin thinning, skin thinning, and general degradation, visible signs of skin aging and environmental damage,

Inactive Publication Date: 2002-08-06
THE PROCTER & GAMBLE COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

In a preferred embodiment, the compositions of the present invention comprise a safe and effective amount of a vitamin B.sub.3 compound. The vitamin B.sub.3 compound enhances the skin appearance benefits of the present invention, especially in regulating skin condition, including regulating signs of skin aging, more especially wrinkles, lines, and pores. The compositions of the present invention preferably comprise from about 0.01% to about 50%, more preferably from about 0.1% to about 10%, even more preferably from about 0.5% to about 10%, and still more preferably from about 1% to about 5%, most preferably from about 2% to about 5%, of the vitamin B.sub.3 compound.

Problems solved by technology

Whether extrinsic or intrinsic, these factors result in visible signs of skin aging and environmental damage, such as wrinkling and other forms of roughness (including increased pore size, flaking and skin lines), and other histological changes associated with skin aging or damage.
Extrinsic or intrinsic factors may result in the thinning and general degradation of the skin.
There is also a flattening of the dermal-epidermal junction which results in weaker mechanical resistance of this junction.
Current retinoid formulations, however, can be drying and irritating and result in excessive peeling.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

A stable topical composition is prepared from the following ingredients using conventional formulating techniques.

Ingredient Weight Percent Phase A DI water 14.699 glycerin 10.000 Phase B Carbopol 954 0.400 disodium EDTA 0.100 Phase C isopropyl palmitate 0.400 cetyl alcohol 2.300 cyclomethicone / 1.900 dimethicone copolyol stearyl alcohol 1.500 dimethicone (200 cts) 0.600 PEG 100 Stearate 0.300 stearic acid 0.300 cetyl palmitate 2.500 Phase D DI water 3.000 sodium hydroxide 0.200 Phase E DI water 8.000 Niacinamide 2.000 Phase F Sodium hydroxy glycinate 0.100 Isopropynyl butylcarbamide 0.100 DI water 0.300 butylene glycol 0.300 Phase G isopropyl palmitate 1.000 retinol 0.050 BHT 0.001 Polysorbate 20 0.050

First, Phase A ingredients are combined and sparged using nitrogen for approximately 15 minutes. Phase B ingredients are then dispersed into Phase A until uniform using propeller type mixing and heated the mixture to about 75.degree. C. In a separate vessel, Phase C ingredients are co...

example 2

A stable topical composition is prepared from the following ingredients using conventional formulating techniques.

Ingredient Weight Percent Phase A DI water disodium EDTA 0.100 glycerin 5.000 Phase B cetyl hydroxy 0.150 ethyl cellulose Phase C cetyl alcohol 0.500 stearyl alcohol 0.500 behenyl alcohol 0.500 cetyl ricinoleate 3.000 Steareth 2 1.000 distearyl dimonium chloride 0.250 myristyl myristate 1.500 caprylic / capric / glyceride 1.500 sucrose cottonate 1.000 Phase D DI water 8.000 niacinamide 2.000 Phase E N,N"-methylene bis [N'- 0.100 [(Hydroxymethyl)-2,5,-dioxy-4- imidazolodinyl]urea] DI water 0.300 Isopropynyl butylcarbamide 0.005 butylene glycol 0.300 Phase F isopropyl palmitate 1.000 retinol 0.050 BHT 0.001 Polysorbate 20 0.050

First, Phase A ingredients are combined and sparged using nitrogen for approximately 15 minutes. Phase B ingredients are then dispersed into Phase A until uniform using propeller type mixing and heated the mixture to about 75.degree. C. In a separate ves...

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PUM

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Abstract

Disclosed are skin care compositions containing retinoids which generally improve the quality of the skin, particularly human facial skin. More particularly, the present invention relates to retinol containing skin care compositions with improved skin compatibility.

Description

TECHNICAL FIELDInvention relates to skin care compositions containing retinoids which generally improve the quality of the skin, particularly human facial skin. More particularly, the present invention relates to retinol containing skin care compositions with improved skin compatibility.BACKGROUND OF THE INVENTIONMany personal care products currently available to consumers are directed primarily to improving the health and / or physical appearance of the skin. Among these skin care products, many are directed to delaying, minimizing or even eliminating skin wrinkling and other histological changes typically associated with the aging of skin or environmental damage to human skin.Skin is subject to insults by many extrinsic and intrinsic factors. Extrinsic factors include ultraviolet radiation (e.g., from sun exposure), environmental pollution, wind, heat, low humidity, harsh surfactants, abrasives, and the like. Intrinsic factors include chronological aging and other biochemical change...

Claims

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Application Information

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Patent Type & Authority Patents(United States)
IPC IPC(8): A61K8/67A61K8/30A61K8/14A61K8/00A61K8/40A61K8/49A61Q1/00A61Q1/04A61Q1/06A61Q1/10A61Q1/12A61Q5/02A61Q19/00
CPCA61K8/671A61K2800/52A61Q19/00A61Q19/08
Inventor DECKNER, GEORGE ENDELSANOGUEIRA, JR., JAMES PEDROSAZUKOWSKI, JOSEPH MICHAEL
Owner THE PROCTER & GAMBLE COMPANY