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Manufacturing technique of acanthopanax root soft capsule

A production process, the technology of Acanthopanax senticosus, applied in the direction of capsule delivery, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of backward technology and low bioavailability of human body, and achieve prolonged anesthesia time, stable preparations, The effect of improving the quality of the preparation

Inactive Publication Date: 2007-10-31
HEILONGJIANG FUHE HUAXING PHARMA GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, the finished medicine sold in the market includes Acanthopanax senticosus tablets, which use the natural Chinese medicinal plants of Acanthopanax senticosus, which are extracted and made into extracts, and then dried to make granules. , the technology is relatively backward, and the human bioavailability is low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Liquid preparation

[0027] a. Soak the Acanthopanax senticosus medicinal material with 5 times the amount of 65% ethanol for 12 hours;

[0028] b, reflux extraction for 10 hours and filtration;

[0029] c. The ethanol is recovered from the filtrate, concentrated into an extract, and set aside.

[0030] sol

[0031] a, ethylparaben is dissolved in 90% ethanol;

[0032] b. Add ferric oxide to 4 times the amount of distilled water, and grind it to fine particles with a ball mill;

[0033] c. Weigh gelatin, glycerin, and distilled water and place them in a stainless steel jacketed pot for subsequent use;

[0034] d. Under vacuum stirring, add ferric oxide slurry and ethylparaben alcohol solution, and melt evenly;

[0035] e. Concentrate under reduced pressure to the specified moisture, and turn off the vacuum pump;

[0036] f. Release the glue, filter it with a gauze bag, and put it in an insulated bucket.

[0037] g. Take a sample to measure the moisture and viscos...

Embodiment 2

[0043] Liquid preparation

[0044] a. Soak the Acanthopanax senticosus medicinal material with 8 times the amount of 85% ethanol for 24 hours;

[0045] b, reflux extraction for 15 hours and filtration;

[0046] c. The ethanol is recovered from the filtrate, concentrated into an extract, and set aside.

[0047] sol

[0048] a, ethylparaben is dissolved in 99% ethanol;

[0049] b. Put ferric oxide into distilled water of 8 times the amount, and grind it to fine particles with a ball mill;

[0050] c. Weigh gelatin, glycerin, and distilled water and place them in a stainless steel jacketed pot for subsequent use;

[0051] d. Under vacuum stirring, add ferric oxide slurry and ethylparaben alcohol solution, and melt evenly;

[0052] e. Concentrate under reduced pressure to the specified moisture, and turn off the vacuum pump;

[0053] f. Release the glue, filter it with a gauze bag, and put it in an insulated bucket.

[0054] g. Take a sample to measure the moisture and visc...

Embodiment 3

[0060] Liquid preparation

[0061] a. Soak the Acanthopanax senticosus medicinal material with 7 times the amount of 75% ethanol for 20 hours;

[0062] b, reflux extraction for 12 hours and filtration;

[0063] c. The ethanol is recovered from the filtrate, concentrated into an extract, and set aside.

[0064] sol

[0065] a, ethylparaben is dissolved in 95% ethanol;

[0066] b. Put ferric oxide into distilled water of 6 times the amount, and grind it into fine particles with a ball mill;

[0067] c. Weigh gelatin, glycerin, and distilled water and place them in a stainless steel jacketed pot for subsequent use;

[0068] d. Under vacuum stirring, add ferric oxide slurry and ethylparaben alcohol solution, and melt evenly;

[0069] e. Concentrate under reduced pressure to the specified moisture, and turn off the vacuum pump;

[0070] f. Release the glue, filter it with a gauze bag, and put it in an insulated bucket.

[0071] g. Take a sample to measure the moisture and vi...

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PUM

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Abstract

The soft manyprickle acanthopanax capsule producing process includes soaking manyprickle acanthopanax root in alcohol for 12-24 hr; reflux extraction for 10-15 hr and filtering; recovering alcohol from the filtrate and concentrating the filtrate into extractum; dissolving nipagin an in alcohol; grinding Fe2O3 inside distilled water in a ball mill into fine particle; mixing gelatin, glycerine and distilled water in a sandwiched stainless steel pot; adding Fe2O3 slurry and alcohol solution of nipagin an into the mixture inside the pot under vacuum stirring; decompression concentrating; gauze filtering the liquid mixture; and capsulizing. The manyprickle acanthopanax preparation has high quality and determined curative effect.

Description

Technical field [0001] The invention relates to a production process of Acanthopanax soft capsules. Background technique [0002] At present, the finished medicine sold in the market has Acanthopanax acanthopanax tablets, which use the natural Chinese medicinal plants of Acanthopanax senticosus, which are extracted to make extracts, then dried, and made into granules. , the technology is relatively backward, and the human bioavailability is low. Contents of the invention [0003] The purpose of the present invention is to overcome the above disadvantages and provide a soft capsule production process that can ensure the excellent curative effect of Acanthopanax. [0004] In order to achieve the above object, the technical scheme adopted in the present invention is: [0005] Liquid preparation [0006] a. Soak Acanthopanax medicinal materials with 5-8 times the amount of 65-85% ethanol for 12-24 hours; [0007] b. Reflux extraction for 10-15 hours and filtration; [000...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/254A61K9/48A61P25/20
Inventor 吴光彦吴玉山宁国涛刘宇陈晓伟王玉松
Owner HEILONGJIANG FUHE HUAXING PHARMA GROUP
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