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Chinese medicinal composition for treating heart failure and oral preparation

A heart failure and oral preparation technology, which is applied in the field of traditional Chinese medicine compositions and oral preparations for the treatment of heart failure, can solve the problems of no disease research, no development of new traditional Chinese medicines with unique curative effects, no drugs with very precise curative effects, etc., and achieve curative effect. Reliable, good therapeutic effect, quality controllable effect

Inactive Publication Date: 2007-12-26
惠汝太
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in terms of traditional Chinese medicine treatment in our country, there has been no drug with very definite curative effect. Most of the Chinese patent medicines are based on empirical prescriptions with addition and subtraction of medicinal flavors, combined with Western medicine treatment measures
Neither in-depth research on diseases nor development of new traditional Chinese medicines with unique curative effects

Method used

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  • Chinese medicinal composition for treating heart failure and oral preparation
  • Chinese medicinal composition for treating heart failure and oral preparation
  • Chinese medicinal composition for treating heart failure and oral preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment 1. Preparation of pharmaceutical composition

[0047] Prescription: Astragalus 400g, Salvia miltiorrhiza 170g, Zhifuzi 170g, Poria cocos 170g, Alisma 170g, Tinglizi 170g;

[0048] Preparation method: take 40g of Salvia miltiorrhiza from the above six flavors, grind into fine powder, sterilize, and set aside; add 6 times the amount of 70% ethanol to the remaining five flavors of Danshen ginseng, Astragalus, etc., heat and reflux to extract twice, 1.5 hours each time, filter, Combine the filtrates, recover ethanol under reduced pressure (65-75°C, -0.08Mpa), and continue to concentrate under reduced pressure to a thick paste with a relative density of 1.35 (60°C). Add 8 times the amount of water to the dregs, decoct for 2 hours, filter, and concentrate the filtrate under reduced pressure (65-75°C, -0.08Mpa) to a thick paste with a relative density of 1.35 (60°C). The fine powder is mixed and dried under reduced pressure (65-75°C, -0.08Mpa) to obtain a dry paste...

Embodiment 2

[0049] Embodiment 2. Preparation of pharmaceutical composition

[0050] Prescription: Astragalus 300g, Salvia miltiorrhiza 150g, Zhifuzi 150g, Poria cocos 150g, Alisma 150g, Tinglizi 150g;

[0051] Preparation method: take 30g of Salvia miltiorrhiza for the above six flavors, grind it into fine powder, sterilize, and set aside; add six times the amount of 80% ethanol to each of the remaining five flavors such as Radix Astragali, heat and reflux for 3 times, and filter for 2 hours each time. Combine the filtrates, recover ethanol under reduced pressure (65-75°C, -0.08Mpa), and continue to concentrate under reduced pressure to a thick paste with a relative density of 1.35 (60°C). Add 9 times the amount of water to the dregs, decoct for 3 hours, filter, and concentrate the filtrate under reduced pressure (65-75°C, -0.08Mpa) to a thick paste with a relative density of 1.35 (60°C). The fine powder is mixed and dried under reduced pressure (65-75°C, -0.08Mpa) to obtain a dry paste ...

Embodiment 3

[0052] Embodiment 3. Preparation of pharmaceutical composition

[0053] Prescription: Astragalus 500g, Salvia miltiorrhiza 200g, Zhifuzi 200g, Poria cocos 200g, Alisma 200g, Tinglizi 200g;

[0054] Preparation method: take 50g of Salvia miltiorrhiza from the above six flavors, grind it into fine powder, sterilize, and set aside; add six times the amount of 60% ethanol to each of the remaining Danshen and other five flavors such as astragalus, heat and reflux to extract twice, 1 hour each time, filter, Combine the filtrates, recover ethanol under reduced pressure (65-75°C, -0.08Mpa), and continue to concentrate under reduced pressure to a thick paste with a relative density of 1.35 (60°C). Add 7 times the amount of water to the dregs, decoct for 1 hour, filter, and concentrate the filtrate under reduced pressure (65-75°C, -0.08Mpa) to a thick paste with a relative density of 1.35 (60°C). The fine powder is mixed and dried under reduced pressure (65-75°C, -0.08Mpa) to obtain a ...

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Abstract

A Chinese medicine for treating heart failure by oral taking is prepared from 6 Chinese-medicinal materials including astragalus root, red sage root, prepared aconite root, tuckahoe, etc.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating heart failure and its oral preparation, belonging to the field of traditional Chinese medicine modernization. Background technique [0002] With the acceleration of population aging and the rising incidence of common cardiovascular diseases such as hypertension and coronary heart disease, the prevalence of heart failure (heart failure) is gradually increasing. According to statistics in my country, the number of patients with chronic heart failure is as high as 1.9%, and 3.6 million people suffer from chronic heart failure. The mortality rate of this group of people is 37% within 2 years and 82% within 6 years. Statistics from the United States show that there are 4.9 million heart failure patients in the United States, and there are 400,000 to 700,000 new patients every year. The prevalence of heart failure in the population is about 1.5 to 2.0%, while that of people over...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61K36/714A61K36/53A61K36/481A61K36/31A61K36/076A61K9/14A61K9/16A61K9/20A61K9/48A61K47/36A61P9/04
Inventor 惠汝太宋晓东王继征汪一波王晓建刘哲明德前
Owner 惠汝太
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