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Medicinal composition with synergistic effect

A composition and technology of peony, applied in the field of pharmaceutical compositions with synergistic effect, can solve problems such as no suggestion or attempt, no scientific basis and the like

Active Publication Date: 2009-06-10
YUNNAN BIOVALLEY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] What is even more unfavorable is that so far, the existing technology has not provided scientific basis for the basic issues such as whether ginkgo can be used in combination with peony and whether the mechanism of action of the two is additive, synergistic or antagonistic.
As for whether the two can be used in combination for other diseases (such as diabetes, Alzheimer's disease), there is no similar suggestion or attempt in the prior art

Method used

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  • Medicinal composition with synergistic effect
  • Medicinal composition with synergistic effect
  • Medicinal composition with synergistic effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0311] Example 1 Capsules

[0312] Prescription 1: Take 5 g of Ginkgo biloba extract (purity 97%, containing 24% flavonoids and 6% lactone), 5 g of Radix Paeoniae Rubra extract (containing 20% ​​paeoniflorin);

[0313] Prescription 2: Take 3g of Ginkgo biloba extract (purity: 96%, containing 22% of flavonoids and 5% of lactone), and 8g of Radix Paeoniae Rubra extract (containing 15% of paeoniflorin);

[0314] Prescription 3: Take 8 g of Ginkgo biloba extract (purity 90%, containing 20% ​​of flavonoids and 3% of lactone), 5 g of Radix Paeoniae Rubra extract (containing 10% of paeoniflorin);

[0315] The above three prescriptions adopt the same process to prepare capsules: add starch, mix evenly, granulate, pulverize, sieve, dry to obtain granules, and pack into 20 hard capsules.

[0316] After testing, prescription one: each capsule contains ginkgolide 15mg and paeoniflorin 50mg;

[0317] Prescription 2: Each capsule contains 7.5mg of ginkgolide and 60mg of paeoniflorin;

[...

Embodiment 2

[0319] Example 2 tablet

[0320] Take 8g of ginkgolides and 60g of paeoniflorin, grind them into fine powder and pass through an 80-mesh sieve, add appropriate amount of dextrin, mix well, first wet with 40-60% ethanol, then granulate with starch slurry, sieve and dry at 80°C, Prepare 1000 tablets and coat them. After testing, each tablet contains 8mg of ginkgolide and 60mg of paeoniflorin.

Embodiment 3

[0321] Embodiment 3 soft capsules

[0322] Take 40 g of ginkgo flavonoids and 20 g of paeoniflorin, add them into vegetable oil and mix evenly, use gelatin as the capsule shell material, and press into 1000 soft capsules. After testing, each capsule contains 40 mg of ginkgo flavonoids and 20 mg of paeoniflorin.

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PUM

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Abstract

The present invention relates to a medicinal or functional health-care product composition, its preparation method and application. The composition contains natural plant extract or monomer active component. Said medicine composition can be used for preventing and curing the diseases of diabetes and its complicating disease, senile dementia, angiocardiopathy, cerebrovascular disease, hyperlipemia, fatty liver and others.

Description

technical field [0001] The present invention relates to a drug combination, specifically, a medicinal or functional health product composition containing natural plant extracts or monomers, used for the treatment and / or prevention of cardiovascular and cerebrovascular diseases, diabetes and their complications , senile dementia, brain cell protection, central retinal vein occlusion, hyperlipidemia, fatty liver, as well as the application of drugs for preventing the recurrence of cardiovascular and cerebrovascular diseases and preventing restenosis after angioplasty. Background technique [0002] With the rapid development of modern science, people pay more and more attention to "natural" medicines. In recent years, the medical community has done a lot of work in the research of medicinal plants for the prevention and treatment of cardiovascular and cerebrovascular diseases, diabetes and other diseases, and strengthened the analysis and research of biologically active substan...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/65A61K36/16A61K9/00A61P27/02A61P25/28A61P9/00A61P3/10A61P3/06A61P1/16
Inventor 林艳和潘锡平林谷风
Owner YUNNAN BIOVALLEY PHARMA CO LTD