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Compound medicine containing artificial bezoar and nitroimidazole antibiotics

A technology for cultivating bezoar and nitroimidazoles in vitro, which can be used in antibacterial drugs, drug combinations, and pharmaceutical formulations, and can solve problems such as the incomplete elucidation of the bactericidal mechanism, and achieve ideal combination effects, fast analgesic and anti-inflammatory effects, and complete radical cure Effect

Inactive Publication Date: 2007-08-01
赵建文
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its bactericidal mechanism has not been fully elucidated, and the nitroreductase of anaerobic bacteria plays an important role in the energy metabolism of sensitive strains

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 Bezoar Ornidazole Capsules

[0027] In vitro cultured bezoar 5g

[0028] Ornidazole 250g

[0029] Add pharmaceutical excipients according to the above formula, and can make 1000 capsules according to conventional methods. Each capsule contains 5 mg of in vitro cultured bezoar and 250 mg of ornidazole, the mass ratio of which is 1:50.

Embodiment 2

[0030] Embodiment 2 Niuhuang Tinidazole Capsules

[0031] In vitro cultured bezoar 5g

[0032] Tinidazole 500g

[0033] Add pharmaceutical excipients according to the above formula, and can make 1000 capsules according to conventional methods. Each capsule contains 5 mg of in vitro cultured bezoar and 500 mg of ornidazole, the mass ratio of which is 1:100.

Embodiment 3

[0034] Embodiment 3 Bezoar secnidazole capsules

[0035] In vitro cultured bezoar 5g

[0036] Secnidazole 250g

[0037] Add pharmaceutical excipients according to the above formula, and can make 1000 capsules according to conventional methods. Each capsule contains 5 mg of in vitro cultured bezoar and 250 mg of ornidazole, the mass ratio of which is 1:50.

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PUM

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Abstract

The invention relates to a kind of compound medicine made of vitro cultured ox gallstone and nitroimidazole medicine, the ratio of the two kinds of medicine is 1:1-1000. The invention has combined the traditional Chinese medicine theory and modern pharmacodynamics theory and chosen nitroimidazole antibiotics (with great antibacterial activity) and vitro cultured ox gallstone (with obvious effects of anti-inflammatory and relieving fever) as the main material medicine. The combining effects of the medicine is very good with the advantage of quick to relieve pain and eliminate inflammation, radical cure, difficult to recur and low side effects.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a combination medicine of in vitro cultured bezoar and nitroimidazole antibiotics. This drug is used for the treatment of various anaerobic infections, especially for the treatment of acute wisdom tooth pericoronitis, local alveolar abscess, pulpitis, periapical periodontitis and other diseases. Background technique [0002] Though toothache is not a serious disease, it has a strong impact on people's health, and the number of people suffering from various dental diseases in my country reaches tens of millions at present. In daily life, people are prone to toothache and other dental diseases due to eating whole grains, being attacked by wind and cold, and not paying enough attention to it. Common toothache diseases are as follows: [0003] The most common pulpitis is due to the continuous expansion and deepening of caries, so that it is finally close to or penetrates into the pul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/413A61P1/02A61P31/04A61K31/4164
Inventor 赵建文
Owner 赵建文
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