Collunarium containing vitamin B12
A vitamin and B12 technology, applied in the direction of drug combination, blood disease, extracellular fluid disease, etc., can solve the problems of poor stability and low absorption rate
Active Publication Date: 2010-08-11
ZHEJIANG ASEN PHARMA
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Problems solved by technology
B vitamins available 12 The preparation for intranasal administration has a certain degree of irritation, and the stability is poor and the absorption rate is not high. After exploring, the present invention has found a non-irritating preparation composition, which overcomes the defects of the prior art
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The invention relates to a vitamin B12 collunarium liquid preparation, which is prepared from vitamin B12, adhesion promoter, pH modifier, osmoregulation agent and preservative agent.
Description
Technical field: The invention relates to a pharmaceutical composition, in particular to a nasal drop pharmaceutical composition containing vitamin B12. Background technique: Vitamin B 12 English name: Vitamin B 12 Chemical name: Cyanocobalamin The chemical structural formula is as follows: Vitamin B 12 It is an essential vitamin for cell growth and reproduction, hematopoiesis, synthesis of nucleic acid and nerve myelin lipids, and maintenance of the functional integrity of sheathed nerve fibers. Vitamin B 12 Participate in methyl conversion and folic acid metabolism in the body, promote the conversion of 5-methyltetrahydrofolate into tetrahydrofolate, and act as vitamin B 12 When it is lacking, it can lead to folic acid deficiency and DNA synthesis disorder, affecting the maturation of red blood cells. Since this product can promote the transformation of methylmalonic acid into succinic acid and participate in the tricarboxylic cycle, when it is lacking, it can cau...
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IPC IPC(8): A61K31/714A61K47/32A61K47/16A61K47/10A61K47/12A61K47/34A61K47/38A61P7/06A61P25/00
Inventor 邓金明吴海英
Owner ZHEJIANG ASEN PHARMA
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