Propanoic acid polyhexamethylene guanide and preparation method thereof

Abstract

The invention discloses polyhexamethylene guanidine propionic acid and preparing method thereof. The preparing method employs stepwise synthesis, which includes steps of: sufficiently mixing dicyandiamide and alanine under high temperature to synthesize aminoguanidine propionic acid, mixing the aminoguanidine propionic acid, triethylidenepropyldiamine and initiator under high temperature to synthesize the polyhexamethylene guanidine propionic acid. Advantages of the invention are: sterilization effect is excellent, toxity is actually nontoxic level, effect of sterilization is better than existent technique, due to overcoming strong hygroscopicity in existence, the polyhexamethylene guanidine propionic acid can be produced to stable powder, thereby being widely used in fields such as weave, plastic, daily chemicals and water treatment.

Description

technical field

[0001] The invention relates to a polymer and a preparation method thereof, in particular to a polyhexamethylene guanidine propionate (also known as polyolefinyl guanidine propionate) and a preparation method thereof. Background technique

[0002] The application of guanidine disinfectants has a history of more than 50 years, from 1,6-bis(n-p-chlorohexidine) hexane (also known as chlorhexidine, chlorhexidine) to polyhexaethylene, which was used in the 1950s. Methyl biguanide salts, because of their low degree of polymerization, have weak bactericidal efficacy, high toxicity and irritation, and bacteria are prone to drug resistance, so they have gradually begun to withdraw. Since the 1990s, polyhexamethyleneguanidine salts with higher bactericidal efficacy have been developed internationally. Polyhexamethyleneguanidine phosphate and polyhexamethyleneguanidine hydrochloride have been developed. Polyhexamethyleneguanidine phosphate is highly toxic (LD50>2000...