Novel base materials of cataplasm and its preparing method
A poultice and matrix technology, which is applied in the field of making poultices and substrates for various medical external patches, can solve the problems of inconspicuous ability of slow-release drugs, weak sticking force, poor moisturizing properties, etc. The effect of drug loading, no stimulation, and high permeability
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Embodiment 1
[0031] Prescription and ratio:
[0032] Kabham 5.0g Gum Arabic 10.0g Glycerin 30.0g
[0033] Macrogol 400 5.0g Povidone K30 5.0g Povidone K90 15.0g
[0034] Gelatin 20.0g Sodium Hydroxide 2.0g Purified Water 95.0g
[0035] Preparation method: Mix 5.0g of carbomer with 10.0g of gum arabic; mix 30.0g of glycerin and 5.0g of polyethylene glycol 400, add the mixture of carbomer and gum arabic, mix well, take sodium hydroxide and add appropriate amount of purification Water was dissolved completely and added to the mixture, heated and mixed to obtain phase I; take 5.0 g of povidone K30, 15.0 g of povidone K90, and 20.0 g of gelatin and heat and mix to obtain phase II; Phase II is heated and mixed to obtain.
Embodiment 2
[0038] Preparation:
[0039] Mix 2.0g of carbomer with 20.0g of gum arabic; mix with 20.0g of glycerin and 10.0g of polyethylene glycol 400, add the mixture of carbomer and gum arabic, mix well, take sodium hydroxide and add appropriate amount of purified water to make it completely Dissolve and add to the mixture, heat and mix to obtain phase I; take 10.0 g of povidone K30, 25.0 g of povidone K90, and 10.0 g of gelatin and heat and mix to obtain phase II; heat phases I and II Mix, add azone 4.0g, camphor 2.0g, menthol 2.0 and mix evenly to obtain.
Embodiment 3
[0041] Prescription and ratio:
[0042] Kabham 10.0g Gum Arabic 5.0g Glycerin 60.0g
[0043] Macrogol 400 3.0g Povidone K30 5.0g Povidone K90 5.0g
[0044] Gelatin 40.0g Sodium Hydroxide 4.0g Purified Water 80.0g
[0045] Azone 2.0g Capsicum Extract 5.0g
[0046] Preparation:
[0047]Mix 10.0g of carbomer with 5.0g of gum arabic; mix 60.0g of glycerin and 3.0g of polyethylene glycol 400, add the mixture of carbomer and gum arabic, mix well, take sodium hydroxide and add appropriate amount of purified water to make it completely Dissolve and add to the mixture, heat and mix to obtain phase I; take 5.0 g of povidone K30, 5.0 g of povidone K90, and 40.0 g of gelatin and heat and mix to obtain phase II; mix phase I and phase II , stir and heat, add 2.0g of azone and 5.0g of capsicum extract and mix well to obtain.
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