Medical transdermal patch

Abstract

The invention discloses a medical transdermal patch. The patch sequentially comprises a backing layer, a viscose layer I, a skeleton layer, a viscose layer II and an anti-viscose layer from top to bottom. The skeleton layer is characterized by being made from, by weight, 40-50 parts of a isoborneyl acrylate/isoimperhol/glycerin monooleate/polyethylene glycol monoallyl ether/1-allyl-3-methylimidazole chloride/ 6-O-allyl-beta-cyclodextrin copolymer, 8-12 parts of active ingredients, 4-6 parts of DL-aminocaprolactam amidated alginate, 8-12 parts of a penetration enhancer, 0.01-0.03 part of fusionprotein, and 1-2 parts of transdermal functional Chinese herbal extracts. The medical transdermal patch has an excellent transdermal effect, the air permeability is good, the storage stability is good, no irritation is caused to the skin, drug release can be effectively controlled, the patch takes effect rapidly and the treatment effect is good.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to a medicinal transdermal patch. Background technique [0002] In recent years, with the development of science and technology, the gradual improvement of medical level, and the gradual deepening of people's understanding of transdermal drug delivery, it has become one of the main drug delivery methods generally accepted by people. The drug is administered in the form of application, so that the drug passes through each layer of the skin at a certain speed, and is absorbed by the capillary into the body circulation to produce a systemic or local therapeutic effect, avoiding the "first-pass effect" of the drug on the liver and the decomposition of the gastrointestinal tract, and improving the Therapeutic effect; it can maintain a relatively stable blood drug concentration, avoid peak and valley phenomena, and reduce side effects; it can prolong the administration time, red...

AI Technical Summary

Problems solved by technology

However, experiments have shown that the use of simple acrylic pressure-sensitive adhesives containing functional groups such as carboxyl groups or hydroxyl groups are all irritating to the skin on the back of New Zealand white rabbits, especially the addition of various chemical penetration enhancers in the prescription have different degrees of skin irritation. damage

And if the prescription contains excess sodium hydroxide, it can also cause adverse reactions to the patient's skin

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