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62results about How to "Achieve stimulation" patented technology

Multi-target electric stimulation circuit, electric stimulator and signal output method thereof

ActiveCN111346297AAchieve stimulationStimulus conditioning achievedMedical imagingElectrotherapyBrain rhythmElectrical stimulator
The invention discloses a multi-target electric stimulation circuit, an electric stimulator and a signal output method thereof. The electric stimulation circuit comprises a control module, a pluralityof electroencephalogram acquisition modules and a plurality of stimulation adjustment modules, wherein each electrode is correspondingly provided with one electroencephalogram acquisition module andone stimulation adjustment module, and different electrodes are used for stimulating different targets; the electroencephalogram acquisition modules are used for acquiring electroencephalogram signalson the corresponding electrodes and transmitting the electroencephalogram signals to the control module; the control module is used for acquiring a brain rhythm phase signal according to the receivedelectroencephalogram signals, and outputting a stimulation signal at a set waveform phase point after phase locking is carried out on the brain rhythm phase signal; and the stimulation adjustment modules are used for adjusting an electroencephalogram stimulation signal output to the corresponding electrodes according to the received stimulation signal. Through the technical scheme of the invention, electric stimulation for multiple targets is facilitated, and time-locking matching for electric stimulation for multiple targets is realized.
Owner:XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI

Cranial nerve stimulating device for enhancing cognitive function of brain

The invention provides a cranial nerve stimulating device for enhancing a cognitive function of a brain. The device comprises a frequency tunable high-frequency electromagnetic wave source, a beam shaping unit, an optical fiber coupler, a multi-dimensional fine tuning platform, an optical fiber, and an electrophysiology detecting device. The frequency tunable high-frequency electromagnetic wave source is used for generating high-frequency electromagnetic pulses. The beam shaping unit is used for shaping and focusing the high-frequency electromagnetic pulses generated by the frequency tunable high-frequency electromagnetic wave source to the input end of the optical fiber. The optical fiber coupler is used for fixing the input end of the optical fiber. The multi-dimensional fine tuning platform is used for fine tuning and aligning the input end of the optical fiber and a light spot. The optical fiber is used for receiving the high-frequency electromagnetic pulses and introducing the high-frequency electromagnetic pulses into the cranial nerve system through the output end of the optical fiber. The electrophysiology detecting device is used for detecting the tissue activity after thecranial nerve system is stimulated by the high-frequency electromagnetic pulses. According to the cranial nerve stimulating device for enhancing the cognitive function of the brain, the minimally invasive, high-targeting and high-efficiency regulation and enhancement of the nerve system of an animal are realized by accurately introducing the high frequency electromagnetic signal into the nerve system of the animal.
Owner:NAT INNOVATION INST OF DEFENSE TECH PLA ACAD OF MILITARY SCI

Preparation method of boron-doped diamond film/carbon film composite electrode material

The invention discloses a preparation method of a boron-doped diamond film/carbon film composite electrode material, which is characterized by adopting a conventional diamond film preparation method and comprising the following steps: preparing an insulated diamond film (3) on a non-conductive substrate (2); and preparing a boron-doped diamond film (1) on the other side of the substrate, and partially converting the insulated diamond film into a carbon film (4). Primarily in the preparation of the carbon film, the diamond of the insulated diamond film is partially converted into a non-diamond phase such as graphite and amorphous state carbon under the effect of high temperature and oxygen in a boron source; and the preparation of the carbon film and the preparation of the boron-doped diamond film are performed at the same time. When the composite plane electrode material is in use, electrical stimulation is realized by use of the advantages of low impedance and higher charge storage capacity of the carbon film; and meanwhile, the high signal-to-noise ratio of the boron-doped diamond film is more favorable for detecting electrical signals. Compared with a common electrode preparation method, two electrode materials are prepared on the substrate, and two functions can be realized.
Owner:SICHUAN UNIV

High-throughput microfluidic chip and cell analysis device and method

The invention discloses a high-throughput microfluidic chip and a cell analysis device and method. The high-throughput microfluidic chip comprises a cell observation pool, a stimulant channel, a cell introduction channel, a buffer solution channel and a waste liquid channel, wherein the stimulant channel is connected with the opening of the cell observation pool, the cell introduction channel is connected with the side face of the cell observation pool, the connecting site is close to the opening, the buffer solution channel is connected with the bottom of the cell observation pool, and the waste liquid channel is connected with the opening of the cell observation pool. The cell analysis device comprises the high-throughput microfluidic chip, a signal collection device and electric proportional switching valves, and the channel inlet end of the high-throughput microfluidic chip is connected with independent electric proportional switching valves; the signal collection device is arranged at the cell observation pool and is used for collecting cell signals or imaging cells. The analysis method comprises the following steps: capturing cells, stimulating cells and releasing cells. The chip, the device and the method provided by the invention can be used for achieving high-throughput cell stimulation and analysis in multiple modes.
Owner:HUAZHONG UNIV OF SCI & TECH

Sperm collector with wriggling structure

The invention discloses a sperm collector with a wriggling structure. The sperm collector comprises a driving mechanism, a wriggling mechanism, and a sperm collection rubber sleeve driven by the driving mechanism and the wriggling mechanism. The wriggling mechanism is arranged on a support of the driving mechanism. The wriggling mechanism comprises a second motor fixed in the support of the driving mechanism, driving gears fixed to an output shaft of the second motor, crankshafts linked with the driving gears, limiting shafts, and wriggling pieces penetrating through the crankshafts and the limiting shafts. The crankshafts are driven by the second motor to rotate, so as to drive the wriggling pieces to wriggle in the radial direction. The sperm collection rubber sleeve is fixed in the wriggling mechanism. The wriggling pieces are located on the periphery of the sperm collection rubber sleeve. The sperm collection rubber sleeve is pressed through the radial wriggling of the wriggling pieces. By the adoption of the technical scheme, the sperm collection rubber sleeve is linked with the driving mechanism and the wriggling mechanism, and the sperm collection rubber sleeve can have three motion modes by controlling a first motor and the second motor in a rotating mechanism and the driving mechanism. The wriggling structure is simple in design and stable in operation.
Owner:东莞市夜龙保健用品有限公司

Electronic treatment system, electronic devices contained in electronic treatment system, synchronization method and storage medium

ActiveCN111228646AHigh precisionMeet time precision requirementsElectrotherapyMedical devicesComputer hardwareTimestamp
The invention provides an electronic treatment system, electronic devices contained in the electronic treatment system, a synchronization method and a storage medium, and relates to the technical field of electronic medical treatment. The electronic treatment system comprises an in-vitro electronic device and at least one in-vivo electronic device, wherein each of the at least one in-vivo electronic device is electrically connected with at least one electrode arranged in the body of a patient. Moreover, the synchronization method comprises the steps of acquiring timestamp offset of each electronic device; and realizing time synchronization of each electronic device according to the respective timestamp offset of each electronic device. Timestamp offset of different electronic devices is adopted in the time synchronization process, so that errors caused by timestamp difference in a traditional synchronization mode can be avoided, the time synchronization precision can be improved, particularly, the requirement of medical system data processing on time precision can be met, the accuracy of clinical judgment reference can be ensured, and cooperative work of collection, stimulation, drug delivery and the like of each electronic device is realized.
Owner:NEURACLE TECH CHANGZHOU CO LTD

Human-derived biological tissue material and culture cell stimulation method and device

The invention provides a human-derived biological tissue material and a dynamic culture cell stimulation method and device. The biological tissue material comprises an in-vitro culture matrix and a plurality of moldable cavities capable of accommodating cells to be cultured. In the culture process, the cells are placed in a moldable cavity to secrete an extracellular matrix (ECM). The dynamic culture method comprises the following steps: placing cells in the moldable cavity, and applying different external forces to the cells at different time points to stimulate the cells to secrete ECM. According to different to-be-implanted parts, mechanical forces in different directions, sizes and angles are selected to stimulate cells, so that the cells secrete more ECM and play a shaping role, and a composite biological material of'biological material + shaping cell + ECM 'is formed. The composite biological material becomes an organic integrated body through mechanical stimulation, so that the use of a chemical cross-linking agent is avoided. Cell components (immune components) in the composite material can be removed. The obtained biological tissue materials comprise blood vessels, hernia patches, tendons, cartilages, muscles and the like.
Owner:太阳雨林(厦门)生物医药有限公司

Optical device of flexible implantable neural photoelectrode and its design and fabrication method

The invention discloses an optical device of a flexible implantable nerve photoelectrode, which is arranged on a flexible polymer substrate and includes: an input grating, a waveguide and an output grating, the input grating is a parallel grating for coupling incident light, and the input of the waveguide The end of the waveguide is coupled to the input grating, the output end of the waveguide is coupled to the output grating, and the output grating is a focusing grating, which is used to couple and focus light on the recording electrode to provide optical stimulation with single-cell resolution. The invention also discloses the design and preparation method of the optical device. The optical device of the flexible implantable neural photoelectrode provided by the present invention provides single-cell resolution optical stimulation and in-situ recording through the design of the waveguide and grating; the small size of the device can reduce implant damage, and it has low loss and high Coupling and strong focusing; its high integration is conducive to the realization of multi-channel, high-density nerve stimulation and recording; the use of flexible polymer substrates can reduce the formation of nerve scars and achieve long-term stable work in vivo.
Owner:SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI

Optical device of flexible implantable neural photoelectrode and design and preparation method thereof

The invention discloses an optical device of a flexible implantable neural photoelectrode. The optical device is arranged on a flexible polymer substrate and comprises an input grating, a waveguide and an output grating, wherein the input grating is a parallel grating and is used for coupling incident light; the input end of the waveguide is coupled with the input grating; the output end of the waveguide is coupled with the output grating; and the output grating is a focusing grating and is used for optically coupling and focusing light to irradiate above a recording electrode and providing photostimulation with single cell resolution. The invention also discloses a design and preparation method of the optical device. The optical device of the flexible implantable neural photoelectrode, provided by the invention, has the advantages that photostimulation and in-situ recording with single cell resolution are provided through design of the waveguide and the gratings; the device is small in size, so that implantation damage can be reduced, and the device is low in loss, high in coupling and strong in focusing; the high integration level of the device is beneficial to realizing multichannel and high-density nerve stimulation and recording; and by adopting the flexible polymer substrate, formation of nerve scars can be reduced, and long-term in-vivo stable work is realized.
Owner:SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI

Polluted soil in-situ chemical barrier material and preparation and application thereof

The invention belongs to the technical field of in-situ risk control and remediation of contaminated soil, and particularly relates to an in-situ chemical barrier material for heavy metal, organic and compound contaminated soil, a preparation method of the in-situ chemical barrier material and application of the in-situ chemical barrier material to collaborative control and remediation treatment of the contaminated soil and underground water. The material comprises the following components in percentage by weight: 50-95% of in-situ soil in a polluted area and 5-50% of clay mineral. The chemical barrier layer material provided by the invention has the advantages of convenience in material obtaining, multiple functions, lasting performance, convenience in operation, wide application and the like. In-situ clean soil or soil meeting the landfill disposal standard is used as a main matrix material, the economic cost of materials is saved, meanwhile, clay minerals are added into the barrier material, the permeability coefficient of the barrier mixed material is remarkably reduced, in addition, pollution factors are effectively controlled and reduced in an auxiliary mode through application of active materials in the mixed material, and the environmental pollution is reduced. Therefore, the in-situ risk management and control and disposal targets of the polluted site are realized through multiple functional characteristics.
Owner:辽宁中博生态环境技术有限公司

A method for the automated construction of stable electrocatalytic bacterial biofilms

The invention relates to a method for automatically constructing a stable electrocatalytic bacterial biofilm. The method comprises the following steps: firstly assembling a microbe electrochemical reactor, and connecting circuits, wherein the first circuit is as follows: a fixed resistor is connected between an anode and a cathode in series, and the second circuit is as follows: an adjustable direct-current power supply, an ampere meter and a work contact of a circulating time relay are connected between the cathode and the anode; then injecting a bacteria growth medium solution into an anode chamber, inoculating a bacteria source, prestarting a microbe anode by switching on the first circuit, then controlling pulse current between the anode and the cathode to be gradually increased at preset velocity according to the potential change of the anode by switching on the adjustable direct-current power supply of the second circuit, wherein the pulse current is immediately lowered by 40%-60% when the potential of the anode is increased to a limit value and enters a new round of growth stimulation, and the electrocatalytic bacterial biofilm is completely constructed till the pulse current value reaches a preset current limit value and is stable at the preset current limit value for more than 10 hours. The electrocatalytic bacterial biofilm disclosed by the invention can be stably operated with the relatively high working current.
Owner:YANGZHOU UNIV

Intelligent pre-judging device and method for mistaken aspiration of stroke patient

The invention relates to an intelligent pre-judgment device and method for mistaken inhalation of a stroke patient, and belongs to the technical field of detection instruments, the intelligent pre-judgment device comprises a bottom plate, a stimulation mechanism, an adjusting mechanism, a limiting mechanism and a control system, the stimulation mechanism comprises a shell, an aspirator pump, a gas storage chamber, a refrigerator, a cold air storage chamber and a stimulation head, and the stimulation head is arranged in the cold air storage chamber. The adjusting mechanism comprises a lifting column, a supporting plate, a sliding plate, a horizontal push rod, a fixing base and a rotary push rod. The stroke patient is stimulated through the stimulation mechanism; the spatial position of the stimulation mechanism is adjusted through the adjusting mechanism, so that the accuracy of stimulation operation is ensured; the adjusting mechanism is controlled by the control system, so that the stimulation mechanism can automatically adapt to the position change of the patient and carry out accurate stimulation operation, finally automatic monitoring is achieved, the mouth and throat areas of the patient can be monitored, and whether vomiting behaviors and aspiration risks exist or not is further judged.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV
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