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Traditional Chinese medicinal composition for treating protrusion of the intervertebral disc and preparation method and traditional Chinese medicine preparation

A lumbar intervertebral disc herniation and traditional Chinese medicine preparation technology are applied in the field of preparation of traditional Chinese medicine compositions to achieve the effects of reducing inflammatory mediators and local immune responses, promoting regeneration and eliminating pain.

Inactive Publication Date: 2007-10-17
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are currently no effective therapeutic drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Weigh 15g of zedoary turmeric, pulverize, add water, and place it on a volatile oil extractor for extraction. The resulting volatile oil is included in β-cyclodextrin. During inclusion, the weight ratio of volatile oil, β-cyclodextrin and water is 1:4:60 ; Curcuma dregs and 30g of astragalus, 15g of epimedium, 15g of coix seed and 15g of geranium are extracted with water, the water extract is concentrated and then purified by adding ethanol or chitosan, filtered and concentrated to obtain concentrated solution A; 5g, crushed, added water and processed by homogenization method to obtain solution B; combine solution B and concentrated solution A, and vacuum dry, the obtained powder is mixed with the β-cyclodextrin inclusion compound of zedoary turmeric volatile oil and mixed.

Embodiment 2

[0023] Weigh 20g of zedoary turmeric, pulverize, add water, and place on the volatile oil extractor for extraction. The resulting volatile oil is included in β-cyclodextrin. During inclusion, the weight ratio of volatile oil, β-cyclodextrin and water is 1:10:100 ; Curcuma dregs and 40g of astragalus, 20g of epimedium, 20g of coix seed and 20g of geranium are extracted with water, the water extract is concentrated and purified by adding ethanol or chitosan, filtered and concentrated to obtain concentrated solution A; 10g, crushed, added water and processed by homogenization method to obtain solution B; combine solution B and concentrated solution A, and vacuum dry, the obtained powder is mixed with the β-cyclodextrin inclusion compound of zedoary turmeric volatile oil and mixed.

Embodiment 3

[0025] Weigh 18g of zedoary turmeric, pulverize, add water, and place on the volatile oil extractor for extraction. The resulting volatile oil is included in β-cyclodextrin. During inclusion, the weight ratio of volatile oil, β-cyclodextrin and water is 3:4:100 The turmeric dregs and 45g of astragalus, 18g of epimedium, 16g of coix seed and 16g of geranium are extracted with water, the water extract is concentrated and purified by adding ethanol or chitosan, filtered and concentrated to obtain concentrated solution A; 8g, crushed, added water and processed by homogenization method to obtain solution B; combine solution B and concentrated solution A, and vacuum dry, the obtained powder is mixed with the β-cyclodextrin inclusion compound of zedoary turmeric volatile oil and mixed.

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Abstract

The utility model relates to a Chinese medicinal composition for treating lumbar intervertebral disc protrusion comprising raw materials in weight percentage as follows: astragalus root 30-45%, epimeddium 15-20%, zedoary 15-20%, coix seed 15-20%, herb of common heron's bill 15-20%, ground beetle 5-10%. The invention also relates to a Chinese medicinal formulation for treating lumbar intervertebral disc protrusion comprising 70-90% of the above Chinese medicinal composition for treating the lumbar intervertebral disc protrusion and 10-30% of medicinal adjuvant. The provided Chinese medicinal composition and Chinese medicinal formulation are applicable to lumbar intervertebral disc protrusion, cervical spondylosis, scapulohumeral periarthritis, gonarthritis, spinal canal stenosis and sciatica. In addition, the invention also relates to a method for preparing the above Chinese medicinal composition.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine composition for treating lumbar intervertebral disc herniation and a traditional Chinese medicine preparation thereof; the invention also relates to a preparation method of the traditional Chinese medicine composition for treating lumbar intervertebral disc herniation. Background technique [0002] Low back pain is the most common pain syndrome in people. It often has a negative impact on people's production, work, study and life, and it also brings a heavy burden to the family and society. [0003] Lumbar intervertebral disc herniation is one of the common clinical lumbar diseases, and the incidence rate in the population is about 15.2%. The incidence is mainly due to the degenerative changes in the lumbar intervertebral disc tissue. Under the action of various external forces, the fibrous annulus of the intervertebral disc ruptures and the nucleus pulposus tissue protrudes from the rupture, causing t...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/08A61K9/10A61K9/107A61K9/16A61K9/20A61K9/48A61P19/08A61K35/64
Inventor 施杞王拥军张宁刘梅周泉李晨光周重建
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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