57 results about "Spinal canal stenosis" patented technology

The present invention relates to a preventive and/or therapeutic agent for spinal canal stenosis comprising aldose reductase inhibitory compounds. A representative example of aldose reductase inhibitory compounds is the compound represented by formula (I):

wherein all the symbols represent the same meaning as described in the specification; a salt of its acid when R^3a represents hydrogen, or solvate thereof The therapeutic agent of the present invention is effective for prevention and/or therapy for spinal canal stenosis and the like, such as lumbar spinal canal stenosis.

For the purpose of realizing of a method of minimally-invasive therapy for spinal canal stenosis, it is intended to provide a therapeutic device capable of stationing an interspinous process spacer without the need of large skin incision or ligamentous tissue incision and also without the need of detaching of the paraspinal muscle from the spine. There is provided an interspinous process spacer comprising conoid screw region (2) to be screwed into a processus spinosus interspace; spacer region (3) disposed in the longitudinal direction of the screw region (2); head region (4) capable of free interlocking with a tool arbitrarily; and through-hole (5) passing through the axial centers of screw region (2), spacer region (3) and head region (4). The processus spinosus interspace can be smoothly enlarged by screwing of the screw region (2) into the processus spinosus interspace. The spacer region (3) is pinched upon passing of the screw region (2) through the processus spinosus interspace to thereby attain enlarging and fixing of adjacent processus spinosus interspaces. The interspinous process spacer can be guided to an interspinous position by inserting a guide member in the through-hole (5) provided along the axial centers of screw region (2) and spacer region (3) and carrying out penetration into the body along the guide member.

The invention relates to Jingyaokang rehabilitation plasters. The Jingyaokang rehabilitation plasters contain the following raw materials: safflowers, gum myrrh, folium Apoeynum venetum, heracleum hemsleyanum, semen strychni, semen plantaginis, chaenomeles lagenaria, scorpions, manis pentadactyla, centipedes, herba Lycopodii, Chinese angelica, radix notoginseng, radix aconiti feri, resina draconis, ground beetles, menthol, dung beetles and garden balsam stems. A preparation method of the Jingyaokang rehabilitation plasters comprises the steps: frying all the raw materials with edible oil; after the frying is completed, carrying out filtering to remove decoction dregs, so as to obtain liquid medicine; adding yellow lead into the liquid medicine, and decocting the liquid medicine until the yellow lead is completely dissolved, so as to obtain a semi-finished product; pouring the semi-finished product into water for cooling, and then, fishing out the semi-finished product, thereby obtaining the Jingyaokang rehabilitation plasters. The Jingyaokang rehabilitation plasters and the preparation method thereof have the beneficial effects that all the raw materials in the Jingyaokang rehabilitation plasters disclosed by the invention are organically combined together and exert a synergistic effect, thereby being capable of activating blood circulation to dissipate blood stasis, clearing and activating the channels and collaterals, promoting blood circulation to stop pain and strengthening the muscles and bones; the Jingyaokang rehabilitation plasters have a good treatment effect on bone diseases such as cervical spondylosis, scapulohumeral periarthritis, lumbar and leg ache, intervertebral disc herniation, spinal canal stenosis, numbness of the limbs, arthritis, traumatic injury, lumbar muscle strain and acute pain of bone joints.

The utility model relates to a Chinese medicinal composition for treating lumbar intervertebral disc protrusion comprising raw materials in weight percentage as follows: astragalus root 30-45%, epimeddium 15-20%, zedoary 15-20%, coix seed 15-20%, herb of common heron's bill 15-20%, ground beetle 5-10%. The invention also relates to a Chinese medicinal formulation for treating lumbar intervertebral disc protrusion comprising 70-90% of the above Chinese medicinal composition for treating the lumbar intervertebral disc protrusion and 10-30% of medicinal adjuvant. The provided Chinese medicinal composition and Chinese medicinal formulation are applicable to lumbar intervertebral disc protrusion, cervical spondylosis, scapulohumeral periarthritis, gonarthritis, spinal canal stenosis and sciatica. In addition, the invention also relates to a method for preparing the above Chinese medicinal composition.

The invention mainly relates to bone-strengthening pain-relieving paste which is prepared by traditional Chinese medicines such as garter snake, monkshood, radix aconiti agrestis, rhizoma typhonii, notopterygium root, radix angelicae pubescentis, berba aristolochiae mollissimae, nux vomica, frankincense, myrrh, Syzygium aromaticum, medicinal cyathula root, gallnut, linxian, Radix Stephaniae Tetrandrae, Ligusticum wallichii, Angelica sinensis, RhizomaHomalomenae, galangal, root of common peony, flowers carthami, native copper and maintain pee. The paste provided by the invention has the functions of maintaining and strengthening bones, promoting blood circulation to remove meridian obstruction, drawing out piston and removing stasis, dispersing blood stasis and relieving pain, expelling wind-damp and the like, is clinically applied to symptoms such as hyperostosis, shoulder solid state, traumatic injury, lumbar disc herniation, spinal canal stenosis, strain of lumbar muscles, face-ache and arthralgia of upper and lower limbs, and can be further applied to gynaecological patients with hyperplasia of mammary glands, so that the effect is remarkable. The formula is a pure traditional Chinese preparation which is free from side effect and wide in efficacy range. The preparation method provided by the invention comprises six steps; and medicines are added in steps to be decocted to retain and improve the efficacy to the maximum extent, so that the curative effect of the medicine is ensured. The preparation method is simple, convenient to operate and suitable for popularization and application.

The invention provides a traditional Chinese medicine composition for bone diseases, relating the field of traditional Chinese medicines. The traditional Chinese medicine composition for bone diseases is composed of ginseng, angelica, Achyranthes bidentata, eucommia, Cordyceps sinensis, szechuan aconite, radix clematidis, angelica, pseudo-ginseng, gastrodia elata, earthworm, club moss, nux vomica, radix salviae miltiorrhizae, frankincense, draconis sanguis, safflower, homalomena rhizoma, papaya, red paeonia, spatholobus stem, raw white peony root, myrrh, phellodendron bark, Notopterygium incisum and mulberry twig. The composition is prepared from pure traditional Chinese medicines, does not have any toxic or side effect, and has favorable curative effects on osteoarticular diseases, such as bulging, herniation, prolapse, hyperplasia and curvature straightening of cervical vertebrae, bulging, herniation, prolapse and hyperplasia of lumbar, sciatica, lumbar muscle strains, curvature straightening, hyperosteogeny, knee joint hyperplasia, foot joint hyperplasia, spinal canal stenosis, scoliosis, isthmic spondylolisthesis, ankylosing spondylitis, rheumatoid arthritis, overstrain limb pains/sourness/fatigue/cold, numbness and weakness, various bone joint paints and fiber pains, nerve compression and the like.

The invention relates to a Chinese medicinal preparation for treating vertebra osteoproliferation, disc protrusion and spinal canal stenosis, which is prepared from cassia twig, Ligusticum wallichii, notopterygium root, speranskia herb, buck grass, Sichuan aconite root, dahurian angelica root, notoginseng, safflower, frankincense, myrrh, rhizoma corydalis, zedoary, burred tuber, Cinnamomum cassia, processed aconite root, astragalus root, root of red rooted saliva, rhubarb horsetails, boneol, earthworm, centipede, buthus martensi kirsch through steps of proportioning, disintegrating into 100-200 mesh fines, mixing and stirring homogeneously, making medicinal fines.

The invention relates to a traditional Chinese medicinal composition. An active ingredient for treating hyperplasia and rheumatic diseases comprises the following raw materials in parts by weight: 40-60 parts of olibanum, 50-60 parts of myrrh, 15-20 parts of Ephedra equisetina, 45-50 parts of Ligusticum wallichii, 60-70 parts ofSaposhnikovia divaricata, 40-50 parts of Drynaria fortunei, 30-40 parts of Momordica cochinchinensis,20-30 parts of Angelica dahurica, 30-40 parts of Rhizoma Et Radix Notopterygii, 25-30 parts of Radix angelicae pubescentis,40-50 parts of Chaenomeles speciosa fruit, 40-50 parts of Phryma leptostachya, 40-50 parts of Cyathula officinalis, 30-40 parts of Radix Aconiti, 5-20 parts of resina draconis 1, and 15 parts of Herba Asari. The invention also relates to a patch for treating hyperplasia and rheumatic diseases. The active ingredient provided by the invention has effects of softening hard masses, dispelling blood stasis, relaxing muscles and tendons, activating the collaterals, relieving inflammation and dispersing pathogenic wind, and can be used for timely and effective treatment of cervical hyperplasia, lumbar disc herniation hyperplasia, spinal canal stenosis, knee hyperplasia, synovitis, rheumatism, rheumatoid, and other diseases.

The invention discloses Chinese medicine bone-setting powder based on the hot salt method for remedying rheumatoid bone disease. The bone-setting powder is prepared from 5 to 15 percent of millettia reticulat and fumitory, 8 to 17 percent of wild celery, 3 to 9 percent of frankincense and morinda officinalis, 6 to 13 percent of myrrh and rhizoma ligustici wallichii, 7 to 15 percent of rhizoma drynariae, 5 to 13 percent of cistanche salsa, 3 to 8 percent of borneol and 10 to 12 percent of safflower. The material is ground into coarse powder; put into a pure cotton cloth bag and then sealed for thermohaline applying treatment. The invention has the effects of expelling wind and removing damness, trimming bruise, promoting blood circulation and relaxing tendon. The invention has obvious effect on rheumatism, rheumatoid, scapulohumeral periathritis, limb numbness, lumbocrural pain, hyperosteogeny, spinal canal stenosis, proplapse of intervertebral discsciatica, nonunion and aseptic osteonecrosis and no toxic side effects.

The invention provides an external plaster for treating sclerotin diseases such as cervical spondylosis, scapulohumeral periarthritis, lumbar intervertebral disc protrusion, spinal canal stenosis, sciatica, hyperosteogeny, lumbocrural pain, hands and feet numbness and the like, and a plurality of diseases such as wrench and soft tissue injury in clinical. Based on traditional Chinese medicine and pharmacology, the plaster is prepared by the following raw materials according to the weight by parts: 250 parts of gardenia, 100 parts of yam, 100 parts of herba siegesbeckiae, 100 parts of deer bone, 100 parts of asafetida, 500 parts of balm and 100-120 parts of minium by referring modern medicine and folk recipe summed up from several decades of clinical experiences. Clinical observation proves that the medicine has the efficacy of dewetting and dissipating cold, promoting blood circulation by removing blood stasis, clearing and activating the channels and collaterals, and relieving bruises and pains; as the medicine took effect, the symptoms lessened. The total effective rate on the treatment of the symptoms is 98.5% and the recovery rate is 80%. The plaster has unique and novel formulation, precise and lasting drug effect, few components, easy manufacturing, short period of treatment, fast effect, thorough treatment, no relapse, obvious treatment effect and is suitable for clinical popularization.

A method for enhancing the transfection efficiency of naked plasmid DNA in treating and/or preventing angiogenesis-dependent symptoms is provided by the present inventions. According to the present method, a suitable naked plasmid DNA is subjected for intramuscular injection under increased pressure inside the muscle or hyperbaric oxygen. Angiogenesis-dependent symptoms, including wounds, inflammatory diseases, critical limb ischemia, ischemic heart diseases, cerebral infarction, diabetic neuropathy, spinal canal stenosis, etc., may be treated by the present methods.

The invention discloses Chinese herbal medicine liquid for treating lumbar protrusion and spinal canal stenosis and a preparation method thereof, and belongs to the field of Chinese herbal medicines.The Chinese herbal medicine liquid comprises the following raw materials: radix angelicae sinensis, radix saposhnikoviae, radix aconiti, radix aconiti kusnezoffii, cortex eucommiae, caulis sinomenii,herba speranskiae tuberculatae, herba lycopodii, radix achyranthis bidentatae, fructus chaenomelis lagenariae, cassia twig, rhizoma drynariae, radix clematidis, radix gentianae macrophyllae, radix angelicae pubescentis, rhizoma homalomenae, rhizoma chuanxiong, frankincense, myrrh, herba asari, rhizoma zingiberis, radix dipsaci, radix angelicae dahuricae, cortex cinnamomi, cibotium barometz, rheumofficinale, rhizoma curcumae longae, herba ephedrae, erodium stephanianum, fructus liquidambaris, cortex acanthopancis, lignum sappan, rhizoma atractylodis, cortex lycii, borneol, flos carthami, and chinese liquor. The Chinese herbal medicine liquid has obvious treatment effects on lumbar protrusion, spinal canal stenosis, cervical, lumbar and shoulder pain, lumbar muscle strain and joint pain, has effects of relieving pain, promoting blood circulation to remove blood stasis, relaxing channels, activating collaterals and promoting tissue regeneration, is simple in preparation method, is convenient to use through hot compress or fumigation during use, and solves a problem that repeated recurrence cannot be radically treated.

The present invention is a kind of Chinese medicine for treating lumber spinal canal stenosis and belongs to the field of medicine technology. The Chinese medicine is prepared with 20 kinds of Chinese medicinal materials, including deglued antler powder, prepared rhizome of rehmannia, astragalus root, wolfberry fruit, angelica, etc. in certain weight proportion. The Chinese medicine has high effective rate, less toxic side effect, and other advantages.

A remedy for spinal canal stenosis which comprises a combination of a compound having EP2 agonism with a compound having EP3 agonism. A drug comprising a combination of a compound having EP2 agonism with a compound having EP3 agonism shows an efficacy in a rat gait disorder model induced by compression of cauda equina. Namely, it is efficacious against spinal canal stenosis to use a combination of a compound having EP2 agonism with a compound having EP3 agonism or a compound having both EP2 agonism and EP3 agonism.

The pure Chinese medicine preparation for treating rheumatic and rheumatoid diseases is prepared with the material including ginseng, pilose antler, fleeceflower root, aconite root, wild aconite root, safflower, jujube seed, polygala root, dog bone, wine and sugar. The medicine has high curative effect on rheumatic diseases, rheumatoid diseases, spinal canal stenosis and other diseases without relapse.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating rheumatic bone diseases. The traditional Chinesemedicine composition for treating rheumatic bone diseases comprises the following raw materials in parts by weight: 6-10 parts of zaocys dhumnade, 10-15 parts of tinospora sinensis merr, 10-15 partsof pawpaw, and 3-6 parts of pseudo-ginseng. The traditional Chinese medicine composition for treating rheumatic bone diseases is prepared by utilizing stir-frying and modern bioengineering technologies, and has the effects of activating collaterals, relieving pain, promoting blood circulation, dredging governor meridians, tonifying kidney, dredging collaterals, dispelling wind and eliminating arthralgia. The traditional Chinese medicine composition for treating rheumatic bone diseases is mainly used for treating rheumatism, rheumatoid arthritis, cervical spondylosis, scapulohumeral periarthritis, ankylosing spondylitis, lumbar disc herniation and bulging, femoral head necrosis, synovitis, meniscus injury, sciatica, spinal canal stenosis, puerperal diseases and other pains and sub-health people.

The invention discloses a waist and leg moxibustion paste and a preparation method thereof. The method comprises the steps that angelica sinensis, chuanxiong rhizome, caulis spatholobi, rhizoma drynariae, semen strychni, herba asari cum radice, sappanwood, semen brassicae, herba lycopodii, unprocessed radix aconiti, unprocessed radix aconiti kusnezoffii, raw rheum officinale and raw radix arisaemaheterophyllum are completely mixed and then put into a cell wall breaking ultrafine low-temperature pulverizer for crushing and subpackaging, wherein 8grams of mixed powder is subpackaged per bag, the caulis spatholobi, cassia twigs, cortex cinnamomi, chuanxiong rhizome, rhizoma curcumae longae, scorpio, centipedes and rhizoma paridis chinensis are completely mixed and then put into the cell wall breaking ultrafine low-temperature pulverizer for crushing and then soaked in wine. The invention relates to the technical field of health care. The waist and leg moxibustion paste and the preparation method thereof achieve the purpose of waist and leg pain relieving, promote blood circulation to remove blood stasis, dredge collaterals and strengthen bone, and have rehabilitation and health careeffects on gout, hyperostosis spurs in the cervical vertebra, lumbar vertebra, knee joints, heels, elbow joints and other parts, slipped disc, spinal canal stenosis, sciatica and chondromalacia patella and symptoms caused by the diseases.