Medicine composition for treating osteoporosis or preventing bone fracture caused by osteoporosis and its application

Abstract

The present invention provides a pharmaceutical composition containing alendronate or the pharmaceutical acceptable salt thereof and parathyroid hormone or the derivatives thereof, the pharmaceutical composition can also be added with vitamin D and calcium salt. The pharmaceutical composition of the present invention can be used for the treatment of osteoporosis, on the one hand, the present invention can inhibit the bone resorption fundamentally, on the other hand, the present invention can increase the bone mass and improve the bone formation, the two-pronged approach can ensure the patients to get the scientific and comprehensive treatment, so as to achieve the purposes of treatment of osteoporosis, the prevention of occurrence of bone fracture and the treatment of the fractures caused by osteoporosis.

Description

technical field

[0001] The invention relates to a pharmaceutical composition for treating osteoporosis or preventing fractures caused by osteoporosis, in particular to a pharmaceutical composition containing alendronic acid or its salt, parathyroid hormone (PTH) or its derivatives The pharmaceutical composition belongs to the technical field of medicine. Background technique

[0002] Osteoporosis is a systemic disease that occurs during the aging process and is characterized by decreased bone mass and destruction of bone microstructure, bone thinning, and decreased number of trabecular bone, resulting in increased bone fragility and prone to fractures. Sexual bone metabolism disorders. When the above phenomena are present and the patient is accompanied by certain clinical symptoms caused by osteoporosis, it is called osteoporosis. Specifically, osteoporosis is a disease characterized by a decrease in the proportion of bone mineral components and bone matrix per unit volume...