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Anti-gout novel medical preparation

A technology of anti-gout and preparations, which is applied in pill delivery, pharmaceutical formulations, drug combinations, etc., and can solve problems such as large side effects and poor curative effect of Chinese patent medicines

Inactive Publication Date: 2011-05-25
邱日辉 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to develop a new drug preparation for the treatment of gout using plants as raw materials in order to overcome the large side effects caused by the current chemical drugs for the treatment of gout and the defects of poor curative effect of Chinese patent medicines

Method used

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Examples

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Effect test

Embodiment 1

[0023] Embodiment 1, the weight ratio of Folium Artemisiae Argyi and Fructus Plantaginis is: 1: 2, see accompanying drawing 1, preparation steps are as follows: a, get 25 grams of fresh Folium Artemisiae Argyi, wash, dry, slice and pulverize, 25~50 meshes after pulverization . B, unmixed 50 grams of Plantago and Folium Artemisiae Argyi powder, c, 75 grams of mixed medicinal material, adopt the water extraction method to process, and the water extraction method is to immerse the pulverized crude drug in 500 milliliters of distilled water, soak 1 hour, d 1. Boil the soaked crude drug for 1 hour, extract the supernatant, e, filter with 4-12 layers of gauze, f, concentrate the water extract to 25 milliliters by heating and concentrating, g, centrifuge at 10000g to remove slag, h, the supernatant is freeze-dried, i, the dry powder is dissolved in 25 milliliters of normal saline, j, sterilized by filtration through a 0.2 micron pore size filter, k, prepared into an anti-gout drug pr...

Embodiment 2

[0024] Embodiment 2, the weight ratio of Folium Artemisiae Argyi and Fructus Plantaginis is: 1: 4, a, get fresh Folium Artemisiae Argyi 25 grams and wash, dry, slice and pulverize, 25~50 orders after pulverizing. B, 100 grams of Semen Plantaginis is not mixed with Folium Artemisiae Argyi powder, c, 125 grams of mixed medical material is weighed, adopts water extraction method to process. The water extraction method is to soak the crushed crude drug in 850 ml of distilled water, soak for 1 hour, d, boil the soaked crude drug for 1 hour, extract the supernatant, e, filter with 4-12 layers of gauze, f, use heating and concentration method Concentrate the water extract to 42 ml, g, centrifuge at 10,000 g to remove slag, h, freeze-dry the supernatant, i, dissolve the dry powder in 42 ml of normal saline, j, filter through a 0.2 micron pore size filter Sterilized by filtration, k, prepared into anti-gout drug preparation, its concentration contains 30 mg of dry weight per milliliter...

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Abstract

The invention relates to the drug technical field and concretely provides a novel drug preparation for resisting the gout. The preparation includes the raw materials of two traditional Chinese medicines of a wormwood leaf and a plantain seed, which are mixed, dipped and boiled for obtaining a water-extract to be filtered, heated, condensed, centrifugally residue removed, freeze-dried, dissolved by normal saline, filtered by a filter membrane and finally made into the novel drug preparation for resisting the gout. The animal text shows that the novel drug preparation of the invention can very effectively reduce the oteracil potassium to induce the uric acid standard in the blood of a mouse with the hyperuricemia and greatly improve and effectively cure the mice of arthrocele and difficult action, and the novel drug is further used for resisting the human gout to take particular effect.

Description

Technical field: [0001] The invention relates to the technical field of medicines, in particular to a new anti-gout drug preparation. Background technique: [0002] There is a substance called purine in the human body, and when its metabolism is disturbed, it will cause gout. Purine undergoes a series of metabolic changes, and the final product is called uric acid. Uric acid has no physiological function in the human body. Under normal circumstances, 2 / 3 of the uric acid produced in the body is excreted by the kidneys, and 1 / 3 is excreted by the large intestine. Uric acid in the body is constantly produced and excreted, so it maintains a certain concentration in the blood. In the process of purine synthesis and decomposition, various enzymes are involved. Due to the disorder of congenital abnormal metabolism of enzymes, the production of uric acid increases or the excretion decreases, which can cause hyperuricemia. When the blood uric acid concentration is too high, uric ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K9/48A61K9/14A61K9/10A61K9/20A61P19/06A61K36/68
Inventor 张南
Owner 邱日辉
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