Traditional Chinese medicinal composition for preparing medicine for preventing and treating gynopathy

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve problems such as unclear mechanism and affecting the scope of clinical application, and achieve the effect of definite curative effect, less toxic and side effects, and overcoming side effects

Active Publication Date: 2008-04-30
广州白云山潘高寿药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently commonly used traditional Chinese medicines include Neiyixiao, Guiling Capsules, Xuejiesan, etc. They all suspect that their modern mechanism of action is unclear, which affects the scope of clinical application.
The Chinese medicine that carries out systemic multi-target treatment endometriosis like the present invention has not yet seen bibliographical information

Method used

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  • Traditional Chinese medicinal composition for preparing medicine for preventing and treating gynopathy
  • Traditional Chinese medicinal composition for preparing medicine for preventing and treating gynopathy
  • Traditional Chinese medicinal composition for preparing medicine for preventing and treating gynopathy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Salvia 15g, Panax notoginseng 5g, Sanleng 8g, Curcuma 5g, Peach kernel 6g, Angelica 5g, Turtle shell 6.1g, Seaweed 12g, Eucommia 5g, Stir-fried Atractylodes macrocephala 8g, Scutellaria barbata 15g, Guizhi 4.5g, the above twelve flavor water Decoction, prepared into medicine, taken three times a day for four to six weeks, used for endometriosis, breast hyperplasia and ovarian cyst.

Embodiment 2

[0042] Danshen 13g, Panax notoginseng 4.3g, Sanleng 6.7g, Zezhu 6g, peach kernel 5.5g, angelica 5g, turtle shell 6.1g, seaweed 15g, Eucommia 5g, fried Atractylodes macrocephala 7.1g, Scutellaria barbata 15g, Guizhi 5g.

[0043] The four medicinal materials of Sanqi, Sanleng, Curcuma and Turtle Shell are respectively crushed into fine powder; the three medicinal materials of angelica, fried Atractylodes macrocephala, and cassia twig are extracted with volatile oil; Concentrate the extract into extract A; extract the dregs of angelica, fried Atractylodes macrocephala, and cassia twigs to extract volatile oil, salvia miltiorrhiza, and sautéed Eucommia ulmoides with ethanol solution, and add peeled peach kernels, seaweed, and barbata to extract with water , take the water extract and concentrate it into extract B; combine extract A and extract B to continue to concentrate into thick extract C, add the fine powder of Panax notoginseng, Sanleng, curcuma, turtle shell and the volatile...

Embodiment 3

[0045] Danshen 18g, Panax notoginseng 6g, Sanleng 9.0g, Curcuma 6.g, Peach Kernel 5.34g, Angelica 4.5g, Turtle Shell 9g, Seaweed 12g, Eucommia 5.5g, Fried Atractylodes 8g, Scutellaria barbata 15g, Guizhi 5g.

[0046] The above twelve flavors are separately or grouped for supercritical CO 2 The active ingredient group or effective part is extracted by the method, and suitable general-purpose excipients are added, and drugs such as capsules, oral liquids, dripping pills, and injections are made according to conventional methods. The capsule, oral liquid, drop pill and injection can be used for endometriosis, breast hyperplasia and ovarian cyst.

[0047] with supercritical CO 2 Extract the effective component group or effective part, effective component by method and macroporous resin adsorption method, and use the effective component for component compatibility.

[0048] Get the concentrate of Example 1, the extract or capsule preparation of Example 2 and 3 entrust the Pharmac...

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Abstract

The invention discloses an application of a traditional Chinese medicine composition. The active ingredients of the traditional Chinese medicine composition are made of raw materials in parts by weight: 12.57-18.85 parts of salvia miltiorrhiza, 4.18-6.28 parts of Sanqi, 6.67-9.03 parts of trigonum, and 4.45 parts of curcuma ~6.01 parts, peach kernel 5.34~7.22 parts, angelica 4.45~6.01 parts, turtle shell 6.07~9.03 parts, seaweed 11.13~15.05 parts, Eucommia 4.71~5.75 parts, fried Atractylodes macrocephala 7.06~8.64 parts, barbata 14.14~17.28 parts, 4.24-5.18 parts of cassia twigs, the traditional Chinese medicine composition can be used to prepare medicines for treating endometriosis, mammary gland hyperplasia and ovarian cysts. The medicine prepared by the traditional Chinese medicine composition of the present invention can be used alone in the treatment of endometriosis, mammary gland hyperplasia, and ovarian cyst, and is also suitable for EMT and ovarian cyst before and after surgery. relapse. Its notable feature is that it overcomes the hormone-like side effects of western medicine and the surgical discomfort caused by multiple lesions.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a traditional Chinese medicine composition used for preparing medicines for preventing and treating gynecological diseases. Background of the invention [0002] Endometriosis (abbreviation: endometriosis, EMT) is a common gynecological disease, since Rokitansky first discovered endometriosis in 1860, it has gone through 145 years. Endometriosis is a frequently-occurring and common disease among women of childbearing age, and the incidence rate shows an obvious upward trend, reaching 10% to 15%. Dysmenorrhea, lower abdominal pain, pelvic mass, and dyspareunia caused by EMT seriously affect women's health and quality of life, and are also one of the main causes of infertility. This benign disease, which behaves like a malignant disease, has long eluded clinicians. For a long time, the research on the etiology and pathogenesis of endometriosis lacks breakthrough prog...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/906A61K9/02A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P15/00A61P15/14A61K35/56
Inventor 魏大华胡燕卢其福刘振民张俊廖雪珍王四元刘晓明
Owner 广州白云山潘高寿药业股份有限公司
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