Preparation of Chinese medicinal composition for treating chronic atrophic gastritis

Abstract

The present invention relates to a preparation method of a traditional Chinese medicine combination for remedying the chronic atrophic gastritis, which chooses the following materials with certain parts by weight of Chinese goldthread rhizome, spreading hedyotis, seabuckthorn oil, corydalis tuber, parched hawthorn fruit, raw wheat germ, chicken gizzard endothelium and dried ginger. The preparation method is that the Chinese goldthread rhizome is crushed into fine powder; naphtha in the dried ginger is extracted; the corydalis tuber, the spreading hedyotis and the parched hawthorn fruit are extracted by ethanol, and medicinal residues after ethanol extraction, ginger medicinal residues, the wheat germ and the chicken gizzard endothelium are decocted in water to be filtered and concentratedas extract for standby; the seabuckthorn oil is mixed with the fine powder of the Chinese goldthread rhizome uniformly and then is mixed with the extract. The present invention has simple and practicable technology; the adaptation diseases of the prepared medicinal preparation are wide; the ethanol adding quantity, the extracting time and the extracting times for filtering ethanol and the water adding quantity, the extracting time and the extracting times for water decocting in an orthogonal test filtration retain each effective component in the medicinal materials with the effect on the adaptation diseases at the maximum, at the same time the lixiviation of ineffective components is reduced, which takes effect of concentrating but not losing effective components, thus reducing the cost.

Description

A preparation method of traditional Chinese medicine composition for treating chronic atrophic gastritis technical field The invention belongs to the technical field of medicines, and in particular relates to a preparation method of a traditional Chinese medicine composition for treating chronic atrophic gastritis. Background technique Chronic atrophic gastritis belongs to the category of epigastric pain. Chinese medicine believes that chronic atrophic gastritis is mostly related to improper diet, internal injuries of the seven emotions, and overwork. The location of the disease is centered on the stomach, but it involves the liver, gallbladder, spleen, and kidney. one. Chronic gastritis is a common clinical disease, wherein chronic atrophic gastritis is difficult to cure, and a certain proportion (7-10%) of chronic atrophic gastritis will eventually develop into gastric cancer. Therefore, how to treat chronic gastritis and prevent the development of gastric cancer is t...

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Problems solved by technology

Compared with western medicines, Chinese patent medicines have certain clinical curative effect in the treatment of chronic atrophic gastritis, but only a few varieties such as Yangyin Qingwei Granules and Moluotan are currently on the market, and they still have the following shortcomings in clinical application: (1) Yangyin Qingwei Granules are composed of Dendrobium, Anemarrhena, Jinglian, Sophora flavescens, Poria cocos, Atractylodes macrocephala, Radix Astragali, etc. It is mainly used for chronic atrophic gastritis with the principle of nourishing yin and clearing the stomach, strengthening the spleen and harmonizing the middle. It belongs to the syndrome of stagnant heat accumulating in the stomach and hurting qi and yin. Although the curative effect is satisfactory, the price is relatively high and the taste is poor; Stomach subduing, invigorating the spleen and eliminating swelling, dredging collaterals and relieving pain, can eliminate chronic atrophic gastritis intestinal metaplasia and atypical hyperplasia, but have no obvious elimination effect on other symptom types. Therefore, its treatment of symptom types is limited and difficult to satisfy The clinical requirements of the majority of patients

The traditional Chinese medicine preparation for treating chronic atrophic gastritis prepared by the existing preparation method has low active ingredient content, general curative effect and limited indications

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