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Evening primrose oil liquid capsule capable reducing blood sugar, blood fat and weight and preparation method thereof

A liquid capsule and lipid-lowering technology, which is applied in the direction of capsule delivery, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc. It can solve problems such as unstable placement, poor taste, and long disintegration time limit

Inactive Publication Date: 2009-01-07
TIANJIN DANXI TCM INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Evening primrose oil has significant hypoglycemic, lipid-lowering, and weight-loss effects, but the existing formulations of evening primrose oil have disadvantages such as complex process, unstable placement, poor taste, or too long disintegration time limit

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0014] Prescription: Evening Primrose Oil 500g

[0015] VE 1g

[0016]

[0017] Makes 1000 capsules

[0018] Operation: Mix the above prescription materials evenly, pour into gelatin-type hollow hard capsules, and seal with gelatin. Take orally, 3 capsules at a time, 2 times a day.

Embodiment approach 2

[0020] Prescription: Evening Primrose Oil 375g

[0021] Vegetable oil 125g

[0022] Lecithin 1g

[0023]

[0024] Makes 1000 capsules

[0025] Operation: Mix the above prescription materials evenly, and pour them into hydroxypropyl methylcellulose-type hollow hard capsules. Take orally, 4 capsules at a time, 2 times a day.

Embodiment approach 3

[0027] Prescription: Evening Primrose Oil 375g

[0028] salad oil 125g

[0029] VE 1g

[0030]

[0031] Makes 1000 capsules

[0032] Operation: Mix the above prescription materials evenly, and pour them into starch-type hollow hard capsules. Take orally, 4 capsules at a time, 2 times a day.

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Abstract

The invention relates to an evening primrose oil liquid capsule for reducing blood sugar, blood lipid and body weight, and a preparation method thereof. The inventive capsule has the the following advantages that: (1) the evening primrose oil which is in a transparent liquid state is used as a principal drug component and filled in hard capsules, so that the principal drug component is administered in form of a solid dosage form and absorbed in form of a liquid dosage form, thereby improving bioavailability; (2) a proper antioxidant such as vitamin E, lecithin, propyl gallate, etc. is added to ensure the stability of the principal drug component; (3) the mouthfeel is remarkably improved, so as to improve compliance of patients; (4) the content of the capsule is liquid which has fast absorption rate and short stomach retention time, so as to reduce the occurrence of adverse effects; (5) the production process is simple and the production cycle is short, so as to reduce cost; and (6) the inventive capsule has transparent liquid content, stable properties, esthetic appearance, good patient compliance, and wide market of applications.

Description

Technical field: [0001] The invention belongs to a traditional Chinese medicine oral preparation, in particular to a liquid capsule preparation for lowering blood sugar, lowering fat and reducing weight. Background technique: [0002] According to a document published by the International Diabetes Federation, in the past 20 years, the number of diabetic patients in the world has increased dramatically from 30 million to 230 million. Among the ten countries with the largest number of diabetic patients in the world, seven are developing countries, and China is at the top of the list. There are currently 50 million diabetics in China, and the number will double in the next two to three years. The World Health Organization predicts that by 2015, Chinese diabetics will exceed 100 million. [0003] The greatest danger of diabetes is mainly manifested in its chronic complications. 96% of diabetic patients suffer from various degrees of chronic complications. Metabolic syndrome is...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K9/48A61K47/36A61K47/38A61K47/42A61K47/44A61P3/04A61P3/06A61P3/10A61K47/22A61K47/24
Inventor 孔伶俐张益胜尹笠佥魏吉城
Owner TIANJIN DANXI TCM INST
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