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Nasal cavity surface preparation

A preparation and nasal cavity technology, which is applied in the field of medicine, can solve the problems of inability to act directly, strong irritation, and easy side effects, etc., and achieve the effect of enhancing vasoconstriction, reducing the generation of mucus, and reducing mucosal swelling

Inactive Publication Date: 2009-02-11
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, traditional Chinese medicine is taken according to prescription decoction, which cannot directly act on the affected part of the nasal mucosa, and the decoction of traditional Chinese medicine is cumbersome, and it is difficult for patients to persist
There are also capsicum paste mixed with capsicum wine extract, belladonna, etc. to prepare capsicum paste for external application on acupoints to treat allergic rhinitis. The medicine also cannot directly act on the affected part of the nasal mucosa, and the curative effect is not very stable.
[0005] The therapeutic effect of capsaicin (capsaicin) on allergic rhinitis has been reported. It has been reported that capsaicin can relieve runny nose and sneezing, reduce the density and number of SP-IR fibers, and achieve the treatment of allergic rhinitis. However, the direct use of capsaicin is more irritating and prone to side effects. At present, there is a lack of a safe, effective, rapid-acting nasal cavity preparation that directly acts on the nasal mucosa to comprehensively control rhinitis symptoms, especially traditional Chinese medicines with low cost. preparation

Method used

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  • Nasal cavity surface preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 Preparation of nasal cavity surface preparation

[0027] Choose dry peppers with bright red peppers as raw materials, remove the stalks and seeds, wash and drain with water;

[0028] Prepare the raw materials according to the weight ratio of vegetable oil and dried chili in a ratio of 40:6; soak the chili in oil for 3 to 5 days, heat to boil on high heat, adjust to low heat and cook for about 3 minutes, then soak for 3 to 5 days and then filter to obtain the liquid. have to.

Embodiment 2

[0029] Example 2 Preparation of nasal cavity surface preparation

[0030] Choose dry peppers with bright red peppers as raw materials, remove the stalks and seeds, wash and drain with water;

[0031] Prepare various raw materials according to the weight ratio of vegetable oil, dried chili and Xanthium at 40:6:2; after soaking the peppers and Xanthium in oil for 3 to 5 days, heat to a boil on high heat, adjust to low heat and cook for about 3 minutes , soak for 3 to 5 days, filter to obtain the liquid, take the liquid and add it to a conventional nasal spray composition to prepare a spray.

Embodiment 3

[0032] Example 3 Preparation of nasal cavity surface preparation

[0033] Choose dry peppers with bright red peppers as raw materials, remove the stalks and seeds, wash and drain with water;

[0034] Prepare various raw materials according to the weight ratio of vegetable oil, dried chili, cocklebur, and pungent flowers in a ratio of 40:6:2:1; Simmer for about 3 minutes, soak for 3 to 5 days, and then filter to obtain a liquid. Take the liquid and add common auxiliary materials in medicine to prepare an ointment.

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PUM

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Abstract

The invention discloses a preparation for the surface of a nasal cavity, which comprises pimiento and medical ingredients commonly used for pharmacy; by being added with medical materials including fructus xanthii, flos magnolia and liquorice, the preparation can be prepared into a rhinitis curing compound preparation which has a good synergetic effect and acts directly on the nasal mucosa, thus being safe and effective, having fast effects, and be capable of comprehensively controlling and thoroughly improving the symptom of allergic rhinitis.

Description

technical field [0001] The invention belongs to the technical field of medicine and relates to a compound medicine preparation, in particular to a nasal cavity surface preparation for treating allergic rhinitis. Background technique [0002] Perennial allergic rhinitis, commonly known as allergic rhinitis (Allergical rhinitis), is an allergic reaction of the nasal mucosa, characterized by paroxysmal and recurrent rhinorrhea, sneezing, nasal congestion and nasal itching. Nasal mucosal edema, typically gray or gray-blue, with temporary or permanent loss of taste and smell. If the edema involves the Eustachian tube, there may be swelling of the ear, or even hearing loss, and the nasal secretion is thin, watery, and internal. Contains eosinophils. Patients often cause nasal mucosal damage due to repeated attacks, causing secondary infection, aggravating the lesion, increased granular polymorphonuclear cells in the mucosa, cell infiltration and fibrous tissue hyperplasia under t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A61K9/00A61K9/06A61K9/127A61P11/02A61P37/08
Inventor 程靖黄嘉言
Owner GUANGDONG PHARMA UNIV
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