Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A mass spectrometer using a dynamic pressure ion source

A mass spectrometer and ion source technology, applied in the field of mass spectrometers, can solve problems such as limited volume and spatial distribution, unsatisfactory, and reduced ion trap analysis performance

Inactive Publication Date: 2010-12-08
SHIMADZU RES LAB EURO
View PDF10 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this arrangement is unsatisfactory because it limits the volume and spatial distribution of samples for analysis and, in particular, prevents the analysis of multiple samples at the same time period
In addition, surface contamination of the ring electrode and end cap electrodes of the ion trap may occur, which reduces the analytical performance of the ion trap

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A mass spectrometer using a dynamic pressure ion source
  • A mass spectrometer using a dynamic pressure ion source
  • A mass spectrometer using a dynamic pressure ion source

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0038] refer to figure 1 , the mass spectrometer includes an ionization region 1 and a mass analysis region 2 housed in a vacuum housing 3 . It will be understood that all of the following embodiments include vacuum housings, but only in figure 1 described in. The ionization region 1 includes a first ion trap 10 for trapping ions generated by a pulsed ion source, and the mass analysis region 2 includes a second ion trap 20 for efficiently receiving and analyzing ions ejected from the first ion trap 10 . The mass analysis region 2 also includes an ion detector D for detecting ions ejected from the second ion trap 20 .

[0039] In this embodiment of the present invention, the first ion trap 10 is a quadrupole linear ion trap, and the second ion trap 20 is a hyperbolic three-dimensional ion trap including a ring electrode 21 and two end cap electrodes 22 , 23 .

[0040] The two ion traps 10, 20 are arranged in series on a common longitudinal axis X-X. The quadrupole linear io...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A mass spectrometer has a pulsed ion source, a first ion trap (10) for trapping ions generated by the pulsed ion source and for locating trapped ions for subsequent ejection from the first ion trap. A pulse of cooling gas is introduced into the first ion trap (10) at a peak pressure suitable for enabling the first ion trap (10) to trap ions. A turbomolecular pump (17) reduces the pressure of cooling gas before the trapped ions are ejected from the first ion trap (1) towards a second ion trap (20) for analysis. The pulsed ion source has a sample plate (14) which forms an end wall of the first ion trap (10).

Description

technical field [0001] The present invention relates to mass spectrometers; in particular, mass spectrometers having pulsed ion sources such as matrix assisted laser desorption ionization (MALDI) ion sources. Background technique [0002] The MALDI ion source has been widely used in biochemical analysis. Typically, a MALDI ion source includes a sample mixed with a radiation absorbing material to form a matrix deposited on the surface of a sample plate; this aids ionization of the sample after the matrix is ​​irradiated by laser pulses. [0003] Known instruments include a MALDI ion source combined with a time-of-flight (TOF) mass spectrometer; however, such instruments are only capable of performing simple mass spectrometry (MS) analysis. Different types of MALDI-MS interfaces have been developed over the past decade in order to combine MALDI ion sources with other, more general types of mass analyzers, or to develop hybrid systems suitable for performing cascaded mass anal...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): H01J49/42H01J49/04
CPCH01J49/062H01J49/0481H01J49/164
Inventor L·丁
Owner SHIMADZU RES LAB EURO
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com