Solid catalyst reaction equipment and running method thereof

Abstract

The invention discloses a solid phase catalyst reactor and a running method thereof. The reactor comprises a reaction vessel and a solid phase catalyst arranged in the reaction vessel. The solid phase catalyst is provided with a first end face, a second end face and a peripheral face extending between the first end face and the second end face, wherein, the peripheral face of the solid phase catalyst is coated with a waterproof membrane. The method comprises the following detailed steps: reaction solution is added into the reaction vessel; the reaction solution is caused to pass through the first end face of the solid phase catalyst and then enters the interior of the reaction vessel and then flows towards the second end face of the solid phase catalyst under the constraint of the waterproof membrane while the reaction solution reacts with the solid phase catalyst and product solution after reaction flows out of the second end face of the solid phase catalyst. The solid phase catalyst reactor and the running method, provided by the invention, can ensure the easy installation and extraction of a reaction column of the solid phase catalyst and can avoid that liquid in the reaction column directly flows out of a column surface and short circuit is caused by deformation / shrinkage of the solid phase catalyst when in running, thereby improving reactive efficiency and running efficiency.

Description

technical field [0001] The invention relates to the technical field of biocatalysts, in particular to a solid-phase catalyst reaction device and an operating method thereof. Background technique [0002] With the development of biotechnology, enzymes are widely used as biocatalysts in industry and other fields. In the above applications, the enzyme or enzyme-containing cells are usually present in an immobilized form. This is because immobilized enzymes or immobilized cells are often more stable than free enzymes and are easily separated from the product for recycling and reuse, as well as easy storage and transportation. [0003] Usually, the immobilized enzyme or immobilized cells are used in the suspension reaction in the form of particles or packed in the container of the reaction device to constitute the stationary phase, and react with the substrate solution flowing between the particles. However, in the above cases, it is generally difficult for the substrate soluti...

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Problems solved by technology

[0008] Second, under some industrial conditions, such as high temperature and long-term operation, the solid-phase enzyme block that constitutes the reaction column will gradually deform / shrink during operation, resulting in a gap between the enzyme block and the container wall, resulting in a short circuit. This makes part of the substrate solution flow away without reacting with the solid-phase enzyme, resulting in low reaction efficiency and also reduces the operating efficiency of the reaction device

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