Technique for preparing oral liquid for cough and asthma of children
A Kechuanling oral liquid and a preparation process technology, applied in the field of traditional Chinese medicine pharmacy, can solve the problems of prolonged operation time, high labor intensity, low boiling point, etc., and achieve the effects of ensuring quality and stability, reducing production costs, and reducing operating pressure
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Embodiment 1
[0018] According to the preparation technology of the children's Kechuanling oral liquid of the present embodiment, the preparation process comprises the steps:
[0019] (1) Extract the original drug liquid: put 625g of bitter almonds, 1875g of gypsum, 1250g of Radix Isatidis, 625g of Radix Glycyrrhizae, and 625g of Trichosanthes trichosanthes in an extraction pot, add water to decoct for 1 hour, and filter; then add 125g of ephedra and 125g of honeysuckle to the above drug residues Add water and decoct for 1 hour, and combine the extracts to obtain the original medicinal solution.
[0020] (2), preparation of extract: filter the original drug solution with a ceramic membrane with a membrane pore size of 200nm, control the filtration pressure at 0.4MPa, and control the temperature at 30°C to 40°C, collect the clear liquid, and concentrate the clear liquid to a relative density of about It is 1.17 (80 ℃), which is the extract.
[0021] (3), preparation of children's Kechuanlin...
Embodiment 2
[0023] According to the preparation process of the children's Kechuanling oral liquid of the present embodiment is as follows:
[0024] (1), extract the former medicinal liquid: with embodiment 1.
[0025] (2), preparation of extract: filter the original drug solution with a ceramic membrane with a membrane pore size of 100nm, control the filtration pressure at 0.3MPa, and control the temperature at 40°C to 45°C, collect the clear liquid, and concentrate the clear liquid to a relative density of about It is 1.17 (80 ℃), namely extract (about 2000ml).
[0026] (3), preparation of children's Kechuanling oral liquid: take the extract, add stevioside and sodium benzoate dissolved in hot purified water, add purified water to 10000ml, stir evenly, and use a tubular ultra- Membrane filtration, filtration pressure 0.1MPa, filtration temperature: 30-40°C, membrane flux: 200-300L / m 2 .h, to obtain the said children's Kechuanling oral liquid.
Embodiment 3
[0028] According to the preparation process of the children's Kechuanling oral liquid of the present embodiment is as follows:
[0029] (1), extract the former medicinal liquid: with embodiment 1.
[0030] (2), preparation of extract: filter the original drug solution with a ceramic membrane with a membrane pore size of 20nm, control the filtration pressure at 0.2MPa, and control the temperature at 15-20°C, collect the clear liquid, and concentrate the clear liquid to a relative density of about 1.17 (80°C), that is the extract (about 2000ml).
[0031] (3), preparation of children's Kechuanling oral liquid: take the extract, add stevioside and sodium benzoate dissolved in hot purified water, add purified water to 100000ml, stir evenly, and use a tubular ultra- Membrane filtration, filtration pressure: 0.1~0.4MPa, filtration temperature: 0℃~40℃, membrane flux: 50~300L / m 2 .h, to obtain the said children's Kechuanling oral liquid.
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