Doped bone repairing material and preparation method thereof

Abstract

The invention provides a doped bone repairing material, comprising the following main ingredients according to weight proportion: 9 to 9.9 portions of calcium polyphosphate body and 0.1 to 1 portion of alkali polyphosphate. The preparation method thereof is as follows: calcium biphosphate and alkali dihydric phosphate are formed at first, then mixed according to the required preparation ratio of the calcium polyphosphate and the portion of alkali polyphosphate in the materials, and forged at high temperature to generate polyreaction; then the material forged at high temperature is quickly cooled and quenched; then the forged material is converted into amorphous calcium polyphosphate and the alkali polyphosphate; then the amorphous calcium polyphosphate and the alkali polyphosphate are dried and ground into powder and then sintered at high temperature, thus manufacturing the crystallized doped bone repairing material. The doped bone repairing material provided by the invention has the characteristics of inorganic and organic characteristics, combination between doped element and calciumn element as well as combination of rigidity and toughness; moreover, the material also has excellent degrading controllable performances. The alkali metal ions released after degrading are innoxious to inner environments; and the inorganic irons can also promote the bone metabolizing, growing and nutrition absorption.

Description

1. Technical field

[0001] The invention relates to the technical field of biomedical materials, in particular to the technical field of biomedical materials suitable for repairing human hard tissue defects. 2. Background technology

[0002] In recent years, research on bone repair materials has focused on establishing ideal models that are non-toxic, harmless, and unchanged to the human body or implanted devices. The widely used artificial bone materials, such as: hydroxyapatite (HA), β-tricalcium phosphate (β-TCP), bioactive glass, bioactive bone cement, etc., can all be connected with human bone and exhibit certain biological characteristics. Capacitance. However, due to differences in biodegradation, osteoinduction, and bone transmission, there is still considerable controversy regarding the search for bone repair materials that adapt to the human physiological environment and have excellent performance. deBruijin et al. believe that the formation of bone-like apatite l...