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Gel patch for treating scapulohumeral periarthritis and preparation method thereof

The technology of frozen shoulder and gel is applied to the gel patch for treating frozen shoulder and the field of preparation thereof, and can solve the problems of low sticking fastness, easy to contaminate clothes, low cohesion and the like

Inactive Publication Date: 2009-07-01
TIANJIN ZHONGBAO PHARMACY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to combine many good prescriptions for treating frozen shoulder, optimize the prescription, integrate the advantages of molecular gel and hydrogel, and overcome the shortcomings of general gel dosage forms such as low fastness, small cohesive force, and easy contamination of clothing.

Method used

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Examples

Experimental program
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Effect test

Embodiment

[0030] Prescription: Chuan Yujin 25kg, Angelica 20kg, Frankincense 15kg, Myrrh 15kg, Borneol 5kg

[0031] Transdermal Penetration Enhancer Laurazone Azone 6kg

[0032] Isopropyl Myristate 2kg

[0033] Molecular Gel 5% Dioctadecyldimethylammonium Chloride

[0034] 70% cyclohexane, 25% 2-ethoxyethanol 100kg

[0035] Hydrogel 8% Sodium Polyacrylate, 2% Polyvinylpyrrolidone

[0036] 2% sodium carboxymethylcellulose, 20% propylene glycol

[0037] 20% glycerol, 1% micronized silica gel, 47% deionized water 400kg

[0038] Medicinal extract 60kg

[0039] Take 70kg of cyclohexane and 25kg of 2-ethylethanol in a stirrer, add 5kg of dioctadecyldimethylammonium chloride and 5kg of medicinal materials to extract volatile oil, heat and stir at 70°C until the mixture is uniform, and gradually cool down until room temperature forms Gel, spare. Take 32kg sodium polyacrylate, 8kg polyvinylpyrrolidone (K90) and 8kg sodi...

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PUM

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Abstract

The present invention discloses a gel patch for treating scapulohumeral periarthritis and a preparing method thereof. The patch of the invention is composed of a back lining layer, an adhesive layer and a protecting layer. The invention is characterized in that the adhesive layer in the patch is mainly prepared through mixing Chinese medicinal herbs, molecular gel, hydrogel and bleeding promoting agent. The composition and weight parts of the Chinese medicinal herbs are as follows: 1-30 parts of Sichuan curcuma aromatica, 1-25 parts of anoelica sinensis, 1-25 parts of frank incense, 1-25 parts of myrrh and 1-20 parts of bornyl alcohol. The weight part of molecular gel is 100-500 parts. The weight part of hydrogel is 100-800 parts. The weight part of transdermal bleeding agent is 3-25 parts. The patch of the invention has the advantages of high transdermal rate, durable medicine releasing, easy using, etc. The clinical symptom of scapulohumeral periarthritis can be remarkably alleviated.

Description

technical field [0001] The invention belongs to the technical field of transdermal drug delivery preparations, and relates to a gel patch for treating frozen shoulder and a preparation method thereof. Background technique [0002] Scapulohumeral periarthritis claims again shoulder arthritis, and this is the chronic inflammation of soft tissues such as shoulder muscle, tendon, synovial bursa and joint capsule. Frozen shoulder is a common shoulder disease, frequently-occurring disease for middle-aged and elderly people, and has a higher incidence rate. The patient manifests shoulder joint pain and shoulder joint dysfunction. If not actively treated, it may cause joint stiffness and partial loss of function in the later stage, affecting normal life and work. [0003] At present, Western medicine can only relieve symptoms with analgesics, which have a short duration of action, are prone to relapse, and have many side effects. Traditional Chinese medicine transdermal preparatio...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/70A61K47/12A61K47/14A61K47/18A61K47/24A61K47/28A61K47/32A61K47/38A61K47/40A61P19/02A61K31/045
Inventor 高惠明方昊周英超李扬
Owner TIANJIN ZHONGBAO PHARMACY
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