Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for extracting and separating turmeric effective ingredient curcumin

A technology of an active ingredient and a separation method, applied in the field of extraction and separation of curcumin, an active ingredient of turmeric, can solve problems such as high technical difficulty, and achieve the effects of large adsorption capacity, high physical and chemical stability, and easy elution

Inactive Publication Date: 2009-07-01
BEIJING HOPE HUGE PHARM SCI
View PDF0 Cites 22 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this method is highly specialized and technically difficult

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0021] The preparation method of curcumin in turmeric comprises the following steps:

[0022] (1) Fresh turmeric slices are 2-3mm thick and 75-126mm3 in size, dried ginger

[0023] The yellow powder is crushed and passed through a 65-mesh sieve.

[0024] (2) Add 8 times the amount of turmeric powder or small granules with a sodium hydroxide solution with a mass fraction of 0.5% - 0.8%, leaching at a temperature of 40 - 50°C, and stir. Extract 2---3 times, 3---4 hours each time.

[0025] (3) Combine the filtrates obtained from each extraction and adjust the concentration.

[0026] (4) Let the adjusted solution stand still, and the supernatant is set aside.

[0027] (5) The supernatant has been treated with a macroporous adsorption resin column, washed with water first, then washed with 0% --- 30% ethanol, discarded the washing liquid, eluted with 50% --- 70% ethanol, collected The eluate is concentrated under reduced pressure and dried in vacuum to obtain a dry powder which...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
purityaaaaaaaaaa
Login to View More

Abstract

The invention discloses a method for extracting and separating curcumin as an effective constituent of turmeric, which belongs to the extraction and separation of traditional Chinese medicine effective constituents and technical application. The structural formula of the compound is as shown in a figure. The method for extracting and separating curcumin comprises the steps of grinding turmeric, adding alkali liquid for cold extraction, filtering, performing column chromatography through macroporous resin, performing gradient elution by use of ethanol and water, collecting eluent, reducing pressure, evaporating, concentrating and vacuum-drying the eluent, and obtaining the effective constituent, namely curcumin. The method has the advantages that the macroporous resin used in the method can be repeatedly utilized, and the method is economical and simple by taking water and ethanol as solvents, can conveniently obtain the extract with the effective constituent content not lower than 90 percent, and is easy to industrialize.

Description

technical field [0001] The invention relates to a method for extracting and separating curcumin, an active ingredient of turmeric, and belongs to the field of extracting active ingredients of natural medicines. [0002] curcumin Background technique [0003] Turmeric is one of the commonly used Chinese, Mongolian and Tibetan medicines in clinic. It is included in "Xinxiu Materia Medica", "Materia Medica", "Compendium of Materia Medica", "Materia Medica Seeking Truth", "Jingzhu Materia Medica" and so on. It has the effects of dispelling blood and promoting qi, promoting menstrual flow and relieving pain. For sternocostal tingling, amenorrhea, lump in the abdomen, rheumatic shoulder and arm pain, tumbling and swelling. , Curcumin is a yellow edible plant pigment, which is extracted from the Chinese herbal medicine turmeric. The main components are about 70% curcumin, about 15% demethoxycurcumin, and about 10% demethoxycurcumin. Curcumin is the main active ingredient...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07C49/255C07C45/78C07C45/79A61K36/9066A61K125/00
Inventor 索志新王翰斌
Owner BEIJING HOPE HUGE PHARM SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com