Method for preparing bisphenol A nanometer silicon gel carrier surface molecule print solid phase extraction filling

Abstract

The invention discloses a method for preparing bisphenol A nanometer silicon gel carrier surface molecule print solid phase extraction filling. Firstly, silanizing agent containing double bonds is grafted on the surfaces of nanometer silicon dioxide beads; secondly, template molecules, functional monomers and crosslinking agents are added into toluene solution containing proper grafted nanometer silicon and catalytic amount evocating agent according to a certain proportion and stirred for polyreaction at temperature of 60 to 70 DEG C and for 15 to 24 hours to generate light-yellow powdery polymer; and finally, templates are eluted from the polymer, and the bisphenol A nanometer silicon gel carrier surface molecule print solid phase extraction filling which has high special selectivity to bisphenol A is obtained. Because the invention adopts the tetrabromobisphenol A and biphenyl diphenol which are analogues of target molecule BPA of as templates, the problem of template leakage is solved. The prepared bisphenol A nanometer silicon gel carrier surface molecule print solid phase extraction filling has high special selectivity to bisphenol A, can collect bisphenol A molecules in trace amount of water sample, and has high recovery ratio and good reproducibility.

Description

Preparation method of molecularly imprinted solid phase extraction filler on the surface of bisphenol A nano silica gel carrier technical field The invention belongs to the field of macromolecular materials, and specifically synthesizes a macromolecular material with a specific recognition ability for bisphenol A molecules by using the surface molecular imprinting technology of nano silica gel carrier. Background technique Bisphenol A (BPA) is an environmental hormone, also known as an extrinsic endocrine disrupting chemical substance, which is a trace chemical substance released into the environment due to human production and activities. They usually enter organisms through the food chain, mimic or block the effects of endogenous estrogen, interfere with the synthesis and metabolism of endogenous hormones or their receptors, cause endocrine disorders, endanger the reproductive function of organisms or cause malignant tumors. Therefore, bisphenol A research is related to ...

AI Technical Summary

Problems solved by technology

In order to overcome the disadvantages of difficult template elution and residual memory in the prior art, the present invention provides a method for preparing molecularly imprinted solid-phase extraction fillers on the surface of bisphenol A nano-silica gel carrier, which has the advantages of easy binding of template molecules, easy elution, and difficult Leakage has the advantages of high selectivity and high extraction efficiency for the phenolic environmental hormone BPA

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