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Novel material for totally nontoxic non-polyvinyl chloride medical perfusion tube and method for manufacturing same

A polyvinyl chloride and new material technology, applied in the field of polymer medical materials, can solve problems such as difficulties, performance defects, performance gaps of infusion tubes, etc., and achieve the effect of large output and moderate production cost

Inactive Publication Date: 2009-09-09
ZHEJIANG SANPO POLYMER
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the overall performance of the medical infusion tubes produced by these two methods is only similar to that of PVC medical infusion tubes, and cannot fully reach or exceed PVC medical infusion tubes. Some performances still have a huge gap compared with PVC, such as transparency, durability Satisfy high temperature sterilization and mechanical properties at the same time
Based on the above flexible methods, foreign countries have introduced non-PVC materials for the production of medical infusion tubes. However, due to the gap in the performance of infusion tube products, in those countries that do not compel the use of non-PVC medical infusion tubes, the current non-PVC materials The promotion and application of quasi-medical infusion tubes are always difficult due to their performance defects
It can be said that so far, no company or research institution in the world has developed a styrene-hydrogenated diene block copolymer medical infusion tube material that is completely equivalent in performance to PVC.

Method used

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  • Novel material for totally nontoxic non-polyvinyl chloride medical perfusion tube and method for manufacturing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The completely non-toxic non-polyvinyl chloride medical infusion tube material uses a partially hydrogenated linear diblock styrene-hydrogenated 1,3-butadiene block copolymer with a molecular weight of 30,000, and the auxiliary raw material is low molecular weight ethylene with a molecular weight of 2,000. -Propylene copolymer and modified natural antioxidant vitamin E. The degree of hydrogenation of the linear diblock styrene-hydrogenated 1,3-butadiene block copolymer was 50%. This new type of material for medical infusion tubes is continuously produced by co-rotating twin-screw extruders. The production method is: 100kg of partially hydrogenated partially hydrogenated linear diblock styrene-hydrogenated 1,3-butadiene block copolymer, 5kg of low molecular weight ethylene-propylene copolymer and 0.01kg of modified vitamin E After being fully compounded, it is added to a co-rotating twin-screw extruder for continuous production. The processing temperature of the screw e...

Embodiment 2

[0022]Completely non-toxic non-polyvinyl chloride medical infusion tube material adopts partially hydrogenated star-shaped diblock styrene-hydrogenated 2-methyl-1,3-butadiene block copolymer with a molecular weight of 40,0000, auxiliary raw materials It is a low molecular weight ethylene-propylene copolymer with a molecular weight of 10,000 and a modified natural antioxidant vitamin E. The degree of hydrogenation of the partially hydrogenated radial diblock styrene-hydrogenated 2-methyl-1,3-butadiene block copolymer was 99.6%. This new type of material for medical infusion tubes is continuously produced by a counter-rotating twin-screw extruder. The manufacturing process is: 100kg of partially hydrogenated radial diblock styrene-hydrogenated 2-methyl-1,3-butadiene block copolymer, 200kg of low molecular weight ethylene-propylene copolymer and 10kg of modified Vitamin E is added to the counter-rotating twin-screw extruder after being fully compounded for continuous production,...

Embodiment 3

[0024] Completely non-toxic non-polyvinyl chloride medical infusion tube material adopts partially hydrogenated star-shaped tri-block styrene-hydrogenated 1,3-butadiene block copolymer with a molecular weight of 300,000, and the auxiliary raw material is a low molecular weight with a molecular weight of 6,000 Ethylene-propylene copolymer and modified natural antioxidant vitamin E. The degree of hydrogenation of the partially hydrogenated radial triblock styrene-hydrogenated 1,3-butadiene block copolymer was 90%. This new type of material for medical infusion tubes is manufactured continuously using a four-screw extruder. The manufacturing process is as follows: 100kg of partially hydrogenated radial triblock styrene-hydrogenated 1,3-butadiene block copolymer, 40kg of low molecular weight ethylene-propylene copolymer and 10kg of modified vitamin E are fully formulated After mixing, it is added to a four-screw extruder for continuous production, and the processing temperature o...

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Abstract

The invention provides a novel material for a totally nontoxic non-polyvinyl chloride medical perfusion tube. The novel material is characterized in that the material contains the following materials according to the weight percentages thereof: 100 parts of styrene-hydrogenation dialkene block copolymer which is partially hydrogenated, 5-200 parts of ethylene-propylene copolymer of low molecular weight, and 0.01-10 parts of modified natural oxidation inhibitor vitamin E. The invention further provides a method for manufacturing the novel material. A medical perfusion tube made of the novel material has the advantages of high transparency, high flexibility, steam and dry-heat resistance superior to the PVC medical perfusion tube, and better than the PVC medical perfusion tube in terms of mechanical performance. The medical perfusion tube made of the novel material is totally nontoxic, can not generate allergy, variation and exclusive reaction to human organizations, has the high temperature resistance, aging resistance and uvioresistant performance, can be directly sterilized through high temperature boiling and ultraviolet rays. The novel material of the medical perfusion tube can completely replace PVC and be used for producing medical perfusion tubes of various specifications.

Description

technical field [0001] The invention relates to a completely non-toxic non-polyvinyl chloride medical infusion tube novel material and a manufacturing method thereof, belonging to the field of polymer medical materials. Background technique [0002] Polyvinyl chloride (PVC) infusion tube has the advantages of unbreakable, high transparency, no kink in normal use, high temperature disinfection resistance and good mechanical properties. For a long time, medical infusion tubes at home and abroad all adopt polyvinyl chloride to produce. However, due to the relatively hard PVC material, plasticizers must be added to make infusion tubes, such as bis(2-ethylhexyl) phthalate (DEHP), epoxy soybean oil, etc., and the former is the most commonly used. During the infusion process, the DEHP of the PVC infusion tube will be released into the infusion solution, which will significantly increase the insoluble particles in the solution; it may also interact with the drug and affect the qual...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L53/02C08L23/16C08K5/138B29C47/92B29C48/92
CPCB29C48/92B29C2948/92704B29C2948/92895
Inventor 周赞斌冯震高书峰程国丽
Owner ZHEJIANG SANPO POLYMER
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