Drug composition having functions of cleaning and bacteriostasis

A technology of antibacterial effect and composition, applied in the field of pharmaceutical composition and its preparation, can solve the problems of slow onset of traditional Chinese medicine, small toxic and side effects, skin irritation, etc.

Inactive Publication Date: 2009-09-23
陈永泰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, there are various cleaning and sterilizing drugs on the market, but most of the western medicines have certain side effects, such as skin irritation, while the existing traditional Ch...

Method used

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  • Drug composition having functions of cleaning and bacteriostasis
  • Drug composition having functions of cleaning and bacteriostasis
  • Drug composition having functions of cleaning and bacteriostasis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] Embodiment 1: powder for external use

[0071] Sophora flavescens 900g Phellodendron 450g Gallnut 450g

[0072] Cnidium 450g Burnet 750g Ice flakes 50g

[0073] Peppermint oil 10ml Dextrin 300g

[0074] Chlorhexidine gluconate 150g;

[0075] Take the five herbs of Sophora flavescens, Phellodendron cortex, Galla gall, Cnidium fruit, Burnet burnet, decoct twice with 10 times the weight of water, filter every 2 hours, combine the decoctions, concentrate at 80°C to a relative density of 1.05, and let stand For 48 hours, take the supernatant, concentrate it into a thick paste, add dextrin, and dry under reduced pressure to obtain a dry extract; take the dry extract, crush it, pass through an 80-mesh sieve, add chlorhexidine gluconate, mix well, and use 85 % ethanol to granulate, granulate through a 14-mesh sieve, blow dry at 50-60°C, granulate, and put into a closed container; take peppermint oil and dissolve it in 95% ethanol, spray it into the granules, and seal; Get t...

Embodiment 2

[0076] Embodiment 2: liniment

[0077] Sophora flavescens 700g Phellodendron 550g Gallnut 350g

[0078] Cnidium 550g Burnet 700g Ice flakes 70g

[0079] Peppermint oil 6ml dextrin 420g

[0080] Chlorhexidine gluconate 80g.

[0081] Take the five medicinal materials of Sophora flavescens, Phellodendron cortex, Galla gall, Cnidium chinensis, and Burnet burnet, add 6 times the weight of water to decoct for 3 hours, filter, combine the decoction, concentrate at 75°C to a relative density of 1.03, let stand for 24 hours, take Concentrate the supernatant into a thick paste, add dextrin, and dry under reduced pressure to obtain a dry extract; take the dry extract, pulverize it, pass through a 70-mesh sieve, add chlorhexidine gluconate, mix well, and spray with a concentration of 80% 13-mesh sieve to granulate, air-dried at 50-60°C, granulated, and put into a closed container; take peppermint oil and dissolve it in 92% ethanol, spray it into the granules, and seal it; take borneol ...

Embodiment 3

[0082] Embodiment 3: lotion

[0083] Sophora flavescens 1100g Phellodendron 350g Gallnut 550g

[0084] Cnidium 350g Burnet 880g Ice flakes 40g

[0085] Peppermint oil 14ml Dextrin 180g

[0086] Chlorhexidine gluconate 200g.

[0087] Take the five herbs of Sophora flavescens, Phellodendron cortex, Galla gall, Fructus Cnidii, and Burnet burnet, add 13 times the weight of water to decoct 3 times, filter every 1 hour, combine the decoctions, concentrate at 82°C to a relative density of 1.03, and let stand After 50 hours, take the supernatant, concentrate it into a thick paste, add dextrin, and dry it under reduced pressure to obtain a dry extract; take the dry extract, crush it, pass through a 90-mesh sieve, add chlorhexidine gluconate, mix well, and spray Ethanol with a concentration of 88%, granulated through a 15-mesh sieve, air-dried at 50-60°C, granulated, and placed in a closed container; peppermint oil was dissolved in ethanol with a concentration of 96%, and sprayed int...

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Abstract

The invention relates to a drug composition applicable to cleaning and bacteriostasis on the human body surface. The drug composition is prepared into external preparations by lightyellow sophora root, amur corktree bark, Chinese gall, common cnidium fruit, garden burnet root and the like; the preparations comprise external powders, liniments and lotions. The composition has stronger functions of cleaning and bacteriostasis, and has stronger functions of bacteriostasis and sterilization to escherichia coli, staphylococcus aureus and candida albicans; and the product is mild and has no toxicity and stimulation.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for cleaning and bacteriostatic human body surface and a preparation method thereof. Background technique [0002] At present, there are various cleaning and sterilizing medicines on the market, but most western medicines have certain side effects, such as skin irritation, while the existing traditional Chinese medicines have disadvantages such as slow onset of action. Still lack a kind of onset quick at present, toxic and side effect is little, the bactericidal, disinfection product that effect is remarkable. Contents of the invention [0003] The object of the present invention is to provide a pharmaceutical composition for cleaning and antibacterial of human body surface; another object of the present invention is to provide a preparation method of the composition. [0004] The object of the invention is to realize...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P31/02A61K35/64A61K31/045A61K31/155
CPCY02A50/30
Inventor 陈永泰
Owner 陈永泰
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