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Medicament for treating the hyperplasia of mammary glands and preparation method thereof

A breast hyperplasia and drug technology, applied in the field of medicine, can solve the problems of indefinite curative effect, incomplete treatment, and large side effects, and achieve the effects of less toxic side effects, high cure rate, and low recurrence rate

Active Publication Date: 2011-09-07
陕西三正医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Mammary gland hyperplasia is a common and frequently-occurring disease among young and middle-aged women. At present, Western medicine mostly advocates the use of hormones and vitamins for treatment, but the curative effect is not yet definite, and the side effects are large. The treatment is not complete and it is easy to relapse.

Method used

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  • Medicament for treating the hyperplasia of mammary glands and preparation method thereof
  • Medicament for treating the hyperplasia of mammary glands and preparation method thereof
  • Medicament for treating the hyperplasia of mammary glands and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] The preparation method of embodiment 1 pharmaceutical tablet of the present invention is to be made by following raw material ratio:

[0072] 150 grams of Bupleurum, 150 grams of turmeric, 150 grams of red peony, 235 grams of Prunella vulgaris, 150 grams of Rhizoma Cyperi, 75 grams of antler gum, 150 grams of orange core, 235 grams of Scrophulariae, 75 grams of Fritillaria, and 150 grams of seaweed.

[0073] The preparation method is:

[0074] 1) The above ten flavors, deer horn glue and Fritillaria fritillaria are crushed into fine powder, and the red peony root is refluxed with 80% ethanol for 3 times, each time for 1.0 hour, the amount of alcohol added is 6 times, the extracts are combined, filtered, and the ethanol is recovered from the filtrate Concentrate under reduced pressure to a thick ointment with a relative density of 1.30-1.35 (80°C); combine the dregs with Bupleurum, Curcuma, Prunella vulgaris, Rhizoma Cyperi, Orange Pit, Scrophulariaceae, and seaweed, add...

Embodiment 2

[0076] The preparation of embodiment 2 pharmaceutical capsules of the present invention

[0077] It is made from the following raw materials:

[0078] 170 grams of bupleurum, 170 grams of turmeric, 170 grams of red peony, 255 grams of Prunella vulgaris, 170 grams of Cyperus cyperi, 85 grams of antler gum, 170 grams of orange core, 255 grams of Scrophulariaceae, 85 grams of Fritillaria, 170 grams of seaweed.

[0079] The preparation method comprises: step 1) is the same as Example 1;

[0080] 2) Pack into capsules.

Embodiment 3

[0081] The preparation of embodiment 3 pharmaceutical granules of the present invention

[0082] It is made from the following raw materials:

[0083] Bupleurum 190g, Turmeric 190g, Paeoniae Rubra 190g, Prunella vulgaris 275g, Rhizoma Cyperi 190g, Antler Gum 95g, Orange Pit 190g, Scrophulariaceae 275g, Fritillaria 95g, Seaweed 190g;

[0084] The preparation method comprises: step 1) is the same as Example 1;

[0085] 2) Add starch, granulate and dry.

[0086]

[0087] Table 2. Effect of Chashao Ruzeng Capsules on Rat Granuloma (X±s)

[0088] group

Number of rats (only)

Granulation weight (mg)

control group

10

111.30±3.86

Rukang Tablets 1.12g / kg

10

94.90±5.55 ※

Chashao Ruzeng Capsules 1.12g / kg

10

80.40±4.74 ※※※

Chashao Ruzeng Capsules 0.56g / kg

10

96.80±6.14 ※

Chashao Ruzeng Capsule 0.28g / kg

10

101.80±5.43

[0089] Table 3. Effects of Chashao Ruzeng Capsules on x...

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Abstract

The invention discloses a medicament for treating the hyperplasia of mammary glands, belonging to the technical field of medicine manufacture. The invention also discloses a preparation method. The medicament comprises the following raw material components: 150 to 190 parts of bupleurum, 150 to 190 parts of curcuma longa, 150 to 190 parts of red peony roots, 235 to 275 parts of prunella vulgaris,150 to 190 parts of rhizoma cyperi, 75 to 95 parts of antler glue, 150 to 190 parts of tangerine seeds, 235 to 275 parts of radix scrophulariae, 75 to 95 parts of fritillary bulb and 150 to 190 partsof seaweed, and is prepared by an ethanol extraction method and a water extraction method. Proved by animal tests, the medicament for treating the hyperplasia of mammary glands has obvious therapeuticaction on the hyperplasia of mammary glands, little toxic side effect, high cure rate and low recurernce rate.

Description

1. Technical field [0001] The invention relates to a medicine, in particular to a medicine for treating mammary gland hyperplasia, which belongs to the technical field of medicine manufacture and includes a preparation method. 2. Background technology [0002] Hyperplasia of the mammary glands is a common disease of young and middle-aged women with periodic breast distending pain and lump in the breast. It occurs in women of childbearing age between 25 and 50 years old, and unmarried women and men also occur. It is a non-inflammatory disease of the breast, which belongs to the category of "breast addiction" in traditional Chinese medicine. Also known as "milk spleen" and "milk accumulation". Traditional Chinese medicine believes that liver failure to dredge and vent, and imbalance of Chong and Ren lead to poor circulation of Qi and blood, stagnation of Qi and blood stasis, and coagulation of phlegm to form breast addiction. "Ulcer Kexin Deji" says: "The tuberculosis in the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P15/14A61K35/32
Inventor 王捷
Owner 陕西三正医药有限公司