Oral transmucosal nicotine dosage form

A technology of nicotine and dosage forms, which is applied in the fields of pill delivery, nervous system diseases, and oral medicine feeding equipment, etc. It can solve the problems of delay in the systemic acceptance of active ingredients and the "thinning" of active ingredients, and achieve the effect of convenient tablet size
CN101563071AInactive Publication Date: 2009-10-21CEPHALON INC +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CEPHALON INC
Publication Date
2009-10-21
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention described herein relates to an oral transmucosal solid dosage form useful in treating nicotine addiction or as a nicotine substitute or replacement. By virtue of the formulation in combination with nicotine, the invention transmucosally delivers an effective amount of nicotine to the recipient while permitting the accomplishing of such, and manufacture of such, using a relatively small, convenient and orally comfortable dosage form (e.g., tablet) size.
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Description

[0001] relevant application data

[0002] This application claims priority to US Provisional Applications 60 / 872,177 and 60 / 872,125, filed December 1, 2006. technical field

[0003] The present invention relates to the field of pharmaceutical dosage forms and methods of treatment. In particular, the invention relates to oromucosal dosage forms comprising nicotine or nicotine derivatives, and methods of using the same for the treatment of nicotine withdrawal. Background technique

[0004] Many nicotine withdrawal products and therapies are known. These products include lozenges, gums, transdermal patches, and the like. Lozenges and gels provide oral delivery of nicotine, while transdermal patch treatments deliver nicotine through the wearer's skin. These systems are based on the premise that a successful smoking cessation process requires control of the cravings associated with nicotine addiction. A commercially available example of a product in the form of oral lozenges ...

Claims

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