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Chinese medicinal composition for treating mental diseases, preparation method, application and quality control thereof

A technology for mental illnesses and compositions, which is applied in drug combinations, nervous system diseases, and pharmaceutical formulations, etc., and can solve the problems of long medication cycle, unclear medicinal value and adverse reactions of cinnabar, realgar, arsenic, and mercury accumulation poisoning And other issues

Inactive Publication Date: 2009-12-02
大连美罗中药厂有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although cinnabar and realgar have been used for thousands of years, due to the limitation of historical conditions, the clinical medicinal value and adverse reactions of cinnabar and realgar are not very clear, and it is urgent to re-evaluate them
[0005] Niuhuang Ninggong Tablets, as a drug for treating mental diseases, generally have a long medication cycle. If used improperly, it is also prone to cumulative poisoning of arsenic and mercury.

Method used

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  • Chinese medicinal composition for treating mental diseases, preparation method, application and quality control thereof
  • Chinese medicinal composition for treating mental diseases, preparation method, application and quality control thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Example 1: Preparation of tablets

[0067] ①Weigh 29.8g forsythia, 5.1g amber, 36.7g rhubarb, 4.9g coptis, 36.5g gypsum, 10.3g cassia stone, 36.5g ocher, 14.6g magnet, and 4.2g of pig gall plaster, crushed nine herbs, over 120 Mesh screen

[0068] ②Crush 3.1g of pearl, 3.0g of artificial bezoar, and 3.4g of borneol, and pass through a 160-mesh sieve;

[0069] ③Gardenia 29.8g, Uncaria 53g, Ophiopogon japonicus 49.6g, Turmeric 37.8g, Dandelion 69g, Radix isatidis 38.4g, Honeysuckle 15.5g, Licorice 49.1g, Trichosanthes 49.1g, Rehmannia glutinosa 37.5g, Scutellaria baicalensis 49.3g, Scrophulariaceae 48.7g, Pueraria lobata 28.9g thirteen flavors were decocted twice with 6 times water, the first time was 2 hours, the second time was 2 hours, combined the decoction, filtered, the filtrate was concentrated into a clear paste, and mixed with step ① Jiuwei powder , Dry into fine powder, add appropriate amount of auxiliary materials, granulate, dry, and granulate;

[0070] ④ Mix the ...

Embodiment 2

[0071] Example 2: Preparation of tablets

[0072] ①Weigh 25.4g forsythia, 4.4g amber, 43.2g scutellariae, rhubarb 31.1g, coptis 4.4g, gypsum 43.2g, stone cassia 8.9g, ochre 43.2g, magnet 17.8g, pig gall plaster 3.6g ten herbs Crush and pass through a 140 mesh sieve;

[0073] ②Crush 2.7g of pearl, 2.8g of in vitro cultured bezoar, and 4.4g of borneol, and pass through a 180-mesh sieve;

[0074] ③Gardenia 25.4g, Uncaria 43.2g, Ophiopogon japonicus 43.2g, Turmeric 34.3g, Dandelion 61g, Radix isatidis 41.9g, Honeysuckle 17.8g, Licorice 43.2g, Trichosanthes 43.2g, Rehmannia 31.1g, Scrophulariaceae 43.2g, 25.4g twelve flavors of Pueraria lobata were decocted twice with 8 times water, the first time was 3 hours, the second time was 1 hour, combined the decoction, filtered, the filtrate was concentrated into a clear paste, mixed with the ten flavor powder in step ①, and dried into Fine powder, add appropriate amount of auxiliary materials, granulate, dry, and granulate;

[0075] ④ Mix the...

Embodiment 3

[0076] Example 3: Preparation of capsules

[0077] ①Weigh 26.5g of Forsythia, 4.7g of amber, 35.4g of rhubarb, 4.9g of coptis, 51g of gypsum, 10.8g of cassia stone, 40.1g of ochre, 20.8g of magnet, and 2.9g of pig gall plaster, crushed nine herbs, and crossed 120 meshes. screen;

[0078] ②Crush 3.2g of pearl, 3.1g of bezoar, and 5.1g of borneol, and pass through a 120-mesh sieve;

[0079] ③Gardenia 27.6g, Uncaria 46.5g, Ophiopogon japonicus 48.7g, Turmeric 40.5g, Dandelion 68g, Radix isatidis 45.5g, Honeysuckle 19.4g, Licorice 48.9g, Trichosanthes 47.5g, Rehmannia glutinosa 34.8g, Scutellaria baicalensis 47.6g, Xuan Ginseng 47.6g, Pueraria lobata 28.7g thirteen flavors add 6 times of water to decoct twice, the first time is 3 hours, the second time is 2 hours, combine the decoction, filter, and concentrate the filtrate into a clear paste, and step ① Jiuwei powder Mix and dry into fine powder;

[0080] ④ Mix the pearl, bezoar, and borneol powder into the powder prepared in step ③, ...

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Abstract

The invention provides a Chinese medicinal composition for treating mental diseases, which is prepared from the following raw material drugs in proportion by weight: bezoar, amber, dandelion, pearl, pig bile, radix isatidis, forsythia fruit, borneol, honeysuckle, liquorice root, coptis root, abalone shell, radix trichosanthis, curcuma, rehmanniae, ochre, scutellaria, gypsum, uncaria stem, rhubarb, magnet, figwort, gardenia, radix puerariae and dwarf lilyturf root. Moreover, the invention also discloses a preparation method, application and a quality control method for the Chinese medicinal composition.

Description

Technical field [0001] The invention relates to the technical field of Chinese patent medicines, and more specifically, to a Chinese medicine composition for treating mental illness and its preparation method, use and quality control. Background technique [0002] Mental illness is a common disease of brain dysfunction caused by various reasons. The most common clinical manifestations are emotional high, sleepless nights, provocative quarrels, nonsense, arrogant spanking, hallucinations, and behavior disorders. Schizophrenia is a common mental illness whose cause has not been fully elucidated. According to data released by the Ministry of Health in 2005, the total number of patients with severe mental illness in my country is as high as 16 million. Among them, the number of patients with schizophrenia is the largest, reaching 6 million, which is equivalent to There is one case in every 60 households, and this number is increasing at a rate of 100,000 per year. This has constitute...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P25/18G01N30/36G01N30/90A61K35/56A61K35/413A61K35/10A61K33/26A61K33/06A61K31/045A61K35/618
Inventor 张成海周文波石桂芳姜伟
Owner 大连美罗中药厂有限公司
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