Process for preparing hesperidin

Abstract

The invention relates to a process for preparing hesperidin, which has simple and convenient operation and less pollution and equipment investment. The process comprises the following steps: adding 3to 10 times of 10-80 percent of alcohol into dried orange peel coarse powder to heat, back flow and extract for one to three times for 2 hours each time; combining extracting liquid and filtering; decompressing filter liquid to recover the alcohol till completion; filtering when the filter liquid is hot, refrigerating for 12 hours and filtering; washing filter residues by water, drying at low temperature and adding 50 percent of alkaline alcohol to dissolve; filtering and adding acid into the filter liquid to neutralize; precipitating sediments and collecting the sediments; recrystallizing thealcohol, washing and drying to obtain the hesperidin. The process for preparing hesperidin has high product purity and is easy to realize industrialization amplification.

Description

technical field

[0001] The invention relates to a method for preparing hesperidin, in particular to a method for extracting hesperidin from plants. Background technique

[0002] Hesperidin (Hesperidin), synonym: tangeridin, hesperidin; molecular formula C 28 h 34 o 15 ; Mainly present in the peel of a variety of plants.

[0003] Studies have shown that hesperidin can reduce the fragility and permeability of capillaries, and is used as an adjuvant treatment for hypertension and capillary hemorrhagic diseases. It has the effect of improving capillary resistance (enhancing the effect of vitamin C), has anti-inflammatory, anti-virus, and has the effect of preventing frostbite and inhibiting the aldehyde reductase of rat eye lens.

[0004] In the prior art, the extraction and separation method of hesperidin mainly adopts organic solvent method, etc., the content of hesperidin obtained by these extraction processes is low, the pollution is serious, and it is not conducive to l...