Mutant microorganism with high ability of producing putrescine and preparation of putrescine using same

A technology of microorganisms and putrescine, applied in biochemical equipment and methods, botany equipment and methods, applications, etc., can solve problems such as complex materials, slowing down of putrescine biosynthesis, and induction of putrescine degradation
CN101679964AActive Publication Date: 2010-03-24KOREA ADVANCED INST OF SCI & TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
KOREA ADVANCED INST OF SCI & TECH
Publication Date
2010-03-24

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Abstract

The present invention relates to a mutant microorganism having a high ability of producing putrescine in which genes associated with the decomposition or use pathway of putrescine are weakened or deleted, in a microorganism having a putrescine production metabolic pathway, and to a method for preparing putrescine with a high yield rate by culturing the mutant microorganism under an anaerobic condition. The mutant microorganism having a high ability of producing putrescine according to the present invention is useful for the high-yield production of putrescine and has broad industrial application.
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Description

technical field

[0001] The present invention relates to a mutant microorganism with high putrescine production capacity and a method for using the microorganism to produce putrescine, in particular to a mutant microorganism with high putrescine production capacity, wherein the genes involved in the putrescine degradation or utilization pathway are inactivated or removal, and a method for cultivating the mutant microorganism to produce putrescine in high yield under anaerobic conditions. Background technique

[0002] Putrescine (or 1,4-butylene diamine), is an important raw material for the production of polyamine-4,6 including nylon-4,6, acrylonitrile produced mainly by adding hydrocyanic acid to acrylonitrile produced on an industrial scale by hydrogenation. The known chemical synthesis processes of this compound require non-renewable petrochemical products as raw materials, and rather severe reaction conditions of temperature and pressure in multiple steps and multiple re...

Claims

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