Cartialgenous all-component uniform freeze-dried preparation and production method thereof

Abstract

The invention aims to provide a uniform preparation which contains all components of cartialgenous. Compared with the conventional cartialgenous decoction tablets which are graded into various specifications such as leucogen tablets, wax tablets, sand tablets, sclerites and the like, the uniform preparation contains the all components, of the cartialgenous, existing in a uniform state, provides a medicinal material or a medicament with uniform quality for a doctor or a sufferer to cure diseases with the cartialgenous, and provides a material base for ensuring a curative effect and preventing the fluctuation of a drug effect. Compared with the modern novel processing technology of crashing the cartialgenous into dry powder after the cartialgenous is freeze-dried, the whole process has no high-temperature process, which effectively protects the activity of components of biological factors, and provides a preparation form which can rapidly absorb micromolecular active substances and peptide components through oral mucosa at the same time. Through technical means of flavor-correction and taste-masking, the mouthfeel of the decoction tablets and the preparation is good and the use compliance is improved.

Description

technical field [0001] The invention relates to a freeze-dried excipient preparation containing active ingredients of traditional Chinese medicines and a production method thereof, in particular to a uniform freeze-dry preparation of all velvet antler components and a production method thereof. Background technique [0002] The medicinal use of velvet antler was first seen in the ancient "Shen Nong's Materia Medica", and Li Shizhen introduced the processing method and medicinal efficacy of velvet antler in more detail in "Compendium of Materia Medica". [0003] Antlers are the young antlers of male deer that have not yet been ossified. Deer antler processing should begin with harvesting the antler. There are basically two ways to get the velvet. One is to use a saw to cut off the scalp, which is called sawing velvet; The removed velvet antler should be washed with water first, and the accumulated blood in the antler should be drawn out. After cutting the velvet, it is nec...

AI Technical Summary

Problems solved by technology

[0009] (2) The traditional velvet grading is a grading of appearance, which is qualitative rather than quantitative, which brings great confusion to doctors and patients. There is no conversion relationship between velvet decoction pieces of different grades. The conversion will cause a huge difference in efficacy when switching between different decoction pieces

[0015] However, traditional freeze-dried excipients have strict requirements on excipients. A certain amount of binder and skeleton support agent must be present to form a high-porosity carrier, and the drug loading is limited. The maximum drug loading per milliliter does not exceed 100 mg.

For 1 to 2 grams of dried velvet antler, or even a larger dosage, it is useless

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